Uveitis associated with juvenile idiopathic arthritis (JIA) typically involves the anterior
chamber segment, follows an indolent chronic course, and presents a high rate of uveitic …

Objective. To report on experience using the anti-interleukin 6 receptor antibody tocilizumab
(TCZ) to treat severe and therapy-refractory uveitis associated with juvenile idiopathic …

Kawasaki disease is an acute systemic vasculitis of unknown etiology. Diagnosis is based
on clinical criteria that include fever, exanthema, conjunctivitis, changes in the extremities, …

Objective GNAO1‐related disorders (OMIM #615473 and #617493), caused by variants in
the GNAO1 gene, are characterized by developmental delay or intellectual disability, …

Purpose. To assess the efficacy and safety of adalimumab in patients with juvenile idiopathic
arthritis (JIA) and associated refractory uveitis. Design. Multicenter, prospective case series. …

Kawasaki disease is an acute self-limited systemic vasculitis common in childhood. Intravenous
immunoglobulin (IVIG) is an effective treatment, and it reduces the incidence of cardiac …

Objective. Cryopyrin-associated periodic syndromes (CAPS) are dominantly-inherited
autoinflammatory diseases. The uncontrolled IL-1β overproduction observed in these patients is …

TNF-alpha-blocking agents (anti-TNF) used in juvenile idiopathic arthritis (JIA) are well
established; however, time to withdraw is unclear. Neither prolonged nor tapering treatment …

Chronic anterior uveitis affects 10–30 % of patients with juvenile idiopathic arthritis (JIA) and
is still a cause of blindness in childhood. In most patients it is asymptomatic, bilateral, and …

Background Osteoporosis incidence in children is increasing due to the increased survival
rate of patients suffering from chronic diseases and the increased use of drugs that can …