Objective: To develop evidence based recommendations for the management of ankylosing
spondylitis (AS) as a combined effort of the ‘ASsessment in AS’ international working group …

Objectives. For effective health care provision, knowledge of disease prevalence is paramount.
There has been no systematic endeavour to establish continent-based AS estimates, …

Tumor necrosis factor-α occupies a central role in rheumatoid arthritis (RA) pathogenesis.
We now report that Interleukin-15 (IL-15) can induce TNF-α production in RA through …

Background Acid suppression with famotidine, a histamine H 2 –receptor antagonist, provides
protection against gastric injury in normal subjects receiving short courses of aspirin or …

Interleukin 15 (IL–15) is a novel cytokine with interleukin–2–like activity. It is also a potent T–lymphocyte
chemoattractant. Rheumatoid arthritis (RA) is a chronic inflammatory disease …

OBJECTIVE: Musculoskeletal ultrasonography allows real-time imaging of joint structures
and may be used to complement clinical examination in rheumatological practice. We …

We have demonstrated spontaneous nitric oxide (NO) production by primary synovial
cultures from rheumatoid (RA) and osteoarthritis patients. Increased NO production followed …

OBJECTIVE: To compare joint and soft tissue aspiration using a conventional technique with
an ultrasound (US) guided technique. METHODS: In the conventional group, 32 joints in 30 …

Objective Joint hypermobility syndrome (JHS) is characterized by an association between
joint hypermobility and musculoskeletal pains, the latter occurring in the absence of any …

Dendritic cells (DCs) comprise heterogeneous subsets of professional antigen-presenting
cells, linking innate and adaptive immunity. Analysis of DC subsets has been hampered by a …