Background: Rhesus monkeys have a high prevalence of obesity and spontaneous type 2
diabetes mellitus after the age of 10 years. These monkeys go through a defined, sequential …

To evaluate whether myocardial performance index detects a subclinical impairment of left
ventricular systolic and diastolic function in patients with early stage of type 2 diabetes, …

The immune response has largely been implicated in the pathogenesis of inflammatory bowel
disease (ulcerative colitis and Crohn’s disease) and immunoglobulin A nephropathy. We …

Kaiser et al reported that etanercept seems to have no effect on rheumatoid nodules after 6
months of treatment (1). Four patients with longstanding seropositive rheumatoid arthritis (RA…

Background Fabry disease is an X-linked lysosomal storage disorder caused by α-galactosidase
enzyme deficiency. We present clinical, biochemical, and histologic findings in children …

The Swiss mouse is considered a satisfactory model for experimental chronic chagasic
myocarditis and there is some evidence of an immunopathologic mechanism in the development …

Growth hormone promotes glomerular lipid accumulation in bGH mice. Background Bovine
growth hormone (bGH) transgenic mice develop progressive glomerulosclerosis and exhibit …

Nephroblastomatosis is a rare preneoplastic lesion defined as the presence of diffuse or
multifocal nephrogenic rests. They are divided into 4 categories: perilobar, intralobar, combined…

Renin-angiotensin system inhibition is a widely accepted approach to initially deal with
proteinuria in IgA nephropathy, while the role of immunosuppressants remains controversial in …

La glomerulonefritis rápidamente progresiva (GNRP) es un síndrome clínico que se caracteriza
por la presencia de signos urinarios de enfermedad glomerular e insuficiencia renal de …