ABSTRACT. Podocin mutations (NPHS2 gene) are responsible for the autosomal recessive
form of steroid-resistant nephrotic syndrome. As a result of a screening for these gene …

ABSTRACT. A total of 179 children with sporadic nephrotic syndrome were screened for
podocin mutations: 120 with steroid resistance, and 59 with steroid dependence/frequent …

BACKGROUND:: Posttransplant recurrence of focal segmental glomerulosclerosis (FSGS)
occurs in a relevant proportion of FSGS patients and represents an important clinical …

Objective. Neutrophil extracellular traps (NET) expose modified antigens for autoantibodies
in vasculitis. Little is known about levels and removal pathways of NET in systemic lupus …

NETs constitute a network of DNA and proteins released by neutrophils in response to
infectious and immunologic triggers.NET proteins are recognized as autoantigens in ANCA …

Aims Anti‐CD20 antibodies are increasingly being used to treat idiopathic nephrotic
syndrome (INS) in children. While they may allow steroid and calcineurin inhibitor withdrawal, …

Minimal Change Disease (MCD) is a clinical condition characterized by acute nephrotic
syndrome, no evident renal lesions at histology and good response to steroids. However, …

ABSTRACT. A plasma factor displaying permeability activity in vitro and possibly determining
proteinuria has been hypothesized in idiopathic focal segmental glomerulosclerosis (FSGS…

Mesenchymal stem cells (MSCs) may be of value in regeneration of renal tissue after damage;
however, lack of biological knowledge and variability of results in animal models limit …

BACKGROUND:: Steroid-resistant nephrotic syndrome (SRNS) with focal segmental
glomerulosclerosis has emerged as a leading cause of end-stage renal failure (ESRF) in children …