Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

We now have the ability to measure a number of different vitamin D metabolites with very
accurate methods. The most abundant vitamin D metabolite, 25-hydroxyvitamin D, is currently …

Preconditioning is a powerful form of (myocardial) protection that follows brief sublethal
ischemia. G-protein-coupled receptors constitute the trigger for entrance to the preconditioned …

Background Very high plasma homocysteine levels are characteristic of homocystinuria, a
rare autosomal recessive disease accompanied by the early onset of generalized …

We used two experimental models to prove that resveratrol (trans-3,4′,5-trihydroxystilbene)
reduces cardiac ischemic-reperfusion injury by means of a nitric oxide- and adenosine-…

Objective Among patients with rheumatoid arthritis (RA), there is a high degree of interindividual
variability in the degree of response to methotrexate (MTX) treatment. This study was …

Acute ischemic stroke may trigger an inflammatory response that leads to increased levels
of C-reactive protein (CRP). High levels of CRP may be associated with poor outcome …

Polymorphisms in folate pathway genes may influence the susceptibility to acute lymphoblastic
leukemia (ALL). DNA was isolated from 245 pediatric ALL patients (cases) and from 500 …

The molecular basis for heart failure is unknown, but oxidative stress is associated with the
pathogenesis of the disease. We tested the hypothesis that the activity of xanthine …

Objective To investigate if erythrocyte-methotrexate-polyglutamate (MTX-PG) concentrations
in patients with rheumatoid arthritis (RA) are associated with disease activity or adverse …