Many patients with chronic pain do not obtain adequate relief or experience unacceptable
side effects from existing treatments. Moreover, even when clinical trials report positive …

A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain
Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting clinical …

Background New drug treatments, clinical trials, and standards of quality for assessment of
evidence justify an update of evidence-based recommendations for the pharmacological …

Patients with neuropathic pain (NP) are challenging to manage and evidence-based clinical
recommendations for pharmacologic management are needed. Systematic literature …

Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the general …

Chronic neuropathic pain, caused by lesions in the peripheral or central nervous system,
comes in many forms. We describe current approaches to the diagnosis and assessment of …

… Author links open overlay panel Robert H. Dworkin PhD a b , Alec B. O'Connor MD c ,
Joseph Audette MD d , Ralf Baron Dr Med e , Geoffrey K. Gourlay PhD f , Maija L. …

A cross-sectional, Internet-based survey was conducted in a nationally representative
sample of United States (US) adults to estimate the point prevalence of chronic pain and to …

Objective. To provide recommendations for the core outcome domains that should be considered
by investigators conducting clinical trials of the efficacy and effectiveness of treatments …

… 1.6 g/m2 over 4 h starting 15 min before cisplatin administration … 2 mg given as subcutaneous
injection 1-3 h before and after administration of VCR. Four weeks after discontinuation of …