[HTML][HTML] Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel

…, GJ Jaffe, JS Louie, RB Nussenblatt… - American journal of …, 2000 - Elsevier
PURPOSE: To provide recommendations for the use of immunosuppressive drugs in the
treatment of patients with ocular inflammatory disorders. PARTICIPANTS: A 12-person panel of …

Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens

…, L Santos, M Sayegh, RB Nussenblatt… - Annual review of …, 1994 - annualreviews.org
… cells, and T cells from the Peyer's patches have been reported to preferentially induce
sIgA + B cells into plasma cells. Peyer's patches have also been shown to be a site where …

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

…, CR Yu, X Liu, RM Mahdi, GL Clarke, RB Nussenblatt… - Nature medicine, 2007 - nature.com
T-helper type 17 cells (T H 17) are implicated in rodent models of immune-mediated diseases.
Here we report their involvement in human uveitis and scleritis, and validate our findings …

Standardizatlon of vitreal inflammatory activity in intermediate and posterior uveitis

RB Nussenblatt, AG Palestine, CC Chan, F Roberge - Ophthalmology, 1985 - Elsevier
Standardization of observations is recognized as fundamental to clinical research. The
methodology for the evaluation of anterior segment inflammatory disease has become well …

The natural history of uveitis

RB Nussenblatt - International ophthalmology, 1990 - Springer
Inflammatory diseases of the eye were known to the ancients, but only recently have the
underlying mechanisms to this problem become better defined. During the middle portion of this …

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

…, LA Rozenszajn, Z Lando, RB Nussenblatt - … (Baltimore, Md.: 1950 …, 1988 - journals.aai.org
Experimental autoimmune uveoretinitis (EAU) is an organ-specific, T lymphocyte-mediated
autoimmune disease, which serves as a model for several human ocular inflammations of an …

An unusually high prevalence of ocular toxoplasmosis in southern Brazil

…, S Silveira, ME Camargo, RB Nussenblatt… - American journal of …, 1992 - Elsevier
Because of the frequency of ocular toxoplasmosis and its occurrence in multiple siblings in
southern Brazil, a population-based household survey was performed to better understand …

Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion

…, Z Li, R Villasmil, D Luger, RB Nussenblatt… - The Journal of …, 2008 - journals.aai.org
Th17 cells require IL-6 and TGFβ for lineage commitment and IL-23 for maintenance.
Unexpectedly, naive IL-6−/− splenocytes stimulated with anti-CD3 and IL-23 produced normal …

Intraocular lymphoma: clinical and histopathologic diagnosis

…, DF Martin, M Burnier Jr, CC Chan, RB Nussenblatt - Ophthalmology, 1993 - Elsevier
Background: Intraocular lymphoma is associated with significant morbidity and mortality, but
early diagnosis and treatment may improve prognosis. Methods: The diagnostic features of …

Birdshot retinochoroidopathy associated with HLA-A29 antigen and immune responsiveness to retinal S-antigen

RB Nussenblatt, KK Mittal, S Ryan, WR Green… - American journal of …, 1982 - Elsevier
Antigen HLA-A29 was present in 16 of 20 patients (80%) with birdshot retinochoroidopathy,
but only in 31 of 418 controls (7.4%) (P < .0001). The relative risk for this disease in persons …