The study of human microvascular endothelial cells has been limited, because these cells
are difficult to isolate in pure culture, are fastidious in their in vitro growth requirements, and …

Important complications in sickle cell anemia occur secondary to vascular occlusion, which
is postulated to be initiated by interactions of erythrocytes with vascular endothelial cells. In …

CD36 is an 88-kDa glycoprotein that has been identified on platelets, monocytes, and some
endothelial cells. Experimental evidence suggests that CD36 mediates the binding of …

OBJECTIVE: We sought to develop a validated, reliable pruritus-specific quality-of-life (QOL)
instrument, ItchyQoL. METHODS: From 21 in-depth interviews with patients with pruritus, we …

Vascular endothelial cell adhesion molecule 1 (VCAM-1) is an adherence molecule that is
induced on endothelial cells by cytokine stimulation and can mediate binding of lymphocytes …

For several decades, dermatologists have utilized azathioprine to treat numerous debilitating
skin diseases. This synthetic purine analog is derived from 6-mercaptopurine. It is thought …

Analyses of receptor-ligand interactions are important to the understanding of cellular adhesion.
Traditional methods of measuring the three-dimensional (3D) dissociation constant (K d …

… Gille, SWCaughman and RASwerlick, unpublished observations). Intriguingly, however,
the Sp1‐dependent complexes still form with HDMEC nucleoproteins in a manner …

Adherence of erythrocytes to vascular endothelium likely contributes to the pathophysiology
of episodic vascular occlusion in patients with sickle cell disease (SCD). In addition, …

Interleukin-18 is a potent inducer of interferon-γ by activated T cells, macrophages, and
monocytes and is synthesized as an inactive precursor. Pro-interleukin-18 must be cleaved by …