Comparison of the effect of denosumab and alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a …

…, M Austin, RB Wagman, R Newmark… - Journal of bone and …, 2009 - academic.oup.com
Denosumab is a fully human monoclonal antibody that inhibits bone resorption by neutralizing
RANKL, a key mediator of osteoclast formation, function, and survival. This phase 3, …

Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate

…, D Lium, S Robbins, R Newmark… - Arthritis & …, 2004 - Wiley Online Library
Objective To determine the potential for additive or synergistic effects of combination
therapy with the selective anti–tumor necrosis factor α agent etanercept and the anti–interleukin‐1 …

Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve‐month, multicenter, randomized, double …

…, L Zhou, W Tsuji, R Newmark… - Arthritis & …, 2008 - Wiley Online Library
… Tsuji and Newmark own stock or stock options in Amgen. … Tsuji and Newmark own
stock or stock options in Amgen. … Tsuji and Newmark own stock or stock options in Amgen. …

[HTML][HTML] Brodalumab, an anti-IL17RA monoclonal antibody, in psoriatic arthritis

…, AD Beaulieu, A Deodhar, R Newmark… - … England Journal of …, 2014 - Mass Medical Soc
Background We assessed the efficacy and safety of brodalumab, a human monoclonal
antibody against interleukin-17 receptor A (IL17RA), in a phase 2, randomized, double-blind, …

A randomized, double-blind, placebo-controlled phase 2 study of brodalumab in patients with moderate-to-severe Crohn's disease

…, C Landers, D Li, C Russell, R Newmark… - Official journal of the …, 2016 - journals.lww.com
Richard Newmark: study design, data analysis and interpretation, and drafting of manuscript.
Nan Zhang: study design, data analysis and interpretation, and drafting of manuscript. Yun …

Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates

…, L Zhou, H Wang, W Tsuji, R Newmark - Annals of the …, 2010 - ard.bmj.com
Objectives To report results of subgroup analyses of bone mineral density (BMD) and bone
turnover markers from a randomised, double-blind, placebo-controlled, phase II study of …

A study to evaluate the safety, tolerability, and efficacy of brodalumab in subjects with rheumatoid arthritis and an inadequate response to methotrexate

K Pavelka, Y Chon, R Newmark, SL Lin… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the efficacy and safety of brodalumab, a human monoclonal antibody
inhibitor of the interleukin 17 receptor, in subjects with rheumatoid arthritis (RA). Methods. …

Mo2083 A randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and efficacy of AMG 827 in subjects with moderate to severe Crohn's …

…, GY Melmed, C Blosch, R Newmark… - …, 2012 - gastrojournal.org
Methods Subjects with moderate to severe CD (Crohn's Disease Activity Index [CDAI]≥ 250
and≤ 450) and evidence of active inflammation (elevated C-reactive protein [CRP], …

Effects of anakinra monotherapy on joint damage in patients with rheumatoid arthritis. Extension of a 24-week randomized, placebo-controlled trial.

B Bresnihan, R Newmark, S Robbins… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: To determine the effects of treatment on the radiologic manifestations of joint
damage in patients with rheumatoid arthritis (RA) who participated in a 24-week extension …

Applications of 19F multidimensional NMR

J Battiste, RA Newmark - Progress in Nuclear Magnetic Resonance …, 2006 - Elsevier
Fluorine (19F) NMR spectra are invaluable in the analysis of fluorine containing compounds
and 19F chemical shift correlations with structure have been used for over 40 years (for …