Primary Sjögren's syndrome with severe central nervous system disease
RK Niemelä, M Hakala - Seminars in arthritis and rheumatism, 1999 - Elsevier
OBJECTIVE:: Central nervous system (CNS) involvement in primary Sjögren's syndrome (pSS)
is controversial with regard to frequency, significance, and etiology. METHODS:: We …
is controversial with regard to frequency, significance, and etiology. METHODS:: We …
Bone oedema predicts erosive progression on wrist MRI in early RA—a 2-yr observational MRI and NC scintigraphy study
…, J Vuotila, R Takalo, A Jartti, RK Niemelä… - …, 2006 - academic.oup.com
Objectives . To investigate if disease assessment by contrast-enhanced dynamic and static
magnetic resonance imaging (MRI) and quantitative nanocolloid (NC) scintigraphy gives …
magnetic resonance imaging (MRI) and quantitative nanocolloid (NC) scintigraphy gives …
Magnetic resonance imaging and magnetic resonance sialography of parotid glands in primary Sjögren's syndrome
RK Niemelä, E Pääkkö, I Suramo… - Arthritis Care & …, 2001 - Wiley Online Library
Objective. To look for structural parotid gland changes on magnetic resonance (MR) imaging
and MR sialography of primary Sjögren’s syndrome (SS) patients and healthy control …
and MR sialography of primary Sjögren’s syndrome (SS) patients and healthy control …
Variability of salivary metabolite levels in patients with Sjögren's syndrome
…, R Lappalainen, L Tjäderhane, RK Niemelä… - Journal of oral …, 2021 - jstage.jst.go.jp
Purpose: To investigate inter-and intra-individual variation in the levels and outputs (concentration
multiplied by salivary flow rate) of salivary metabolites in patients with primary Sjögren…
multiplied by salivary flow rate) of salivary metabolites in patients with primary Sjögren…
[HTML][HTML] Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's Syndrome: a randomized, double-blind, placebo controlled cross-over study
H Seitsalo, RK Niemelä, M Marinescu-Gava… - Journal of Negative …, 2007 - Springer
Background Matrix metalloproteinases (MMPs) are proteolytic enzymes that may contribute
to tissue destruction in Sjögren's syndrome (SS). Low-dose doxycycline (LDD) inhibits MMPs…
to tissue destruction in Sjögren's syndrome (SS). Low-dose doxycycline (LDD) inhibits MMPs…
Comprehensive study of autonomic function in a population with primary Sjögren's syndrome. No evidence of autonomic involvement.
RK Niemelä, M Hakala, HV Huikuri… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: Autonomic neuropathy is associated with increased mortality. Autonomic nervous
system disorders have been described in patients with primary Sjögren's syndrome (SS), …
system disorders have been described in patients with primary Sjögren's syndrome (SS), …
[HTML][HTML] Low-dose doxycycline treatment normalizes levels of some salivary metabolites associated with oral microbiota in patients with primary Sjögren's syndrome
…, H Seitsalo, R Lappalainen, L Tjäderhane, RK Niemelä… - Metabolites, 2021 - mdpi.com
Saliva is a complex oral fluid, and plays a major role in oral health. Primary Sjögren’s
syndrome (pSS), as an autoimmune disease that typically causes hyposalivation. In the present …
syndrome (pSS), as an autoimmune disease that typically causes hyposalivation. In the present …
No signs of autonomic nervous system dysfunction in primary Sjörgen's syndrome evaluated by 24 hour heart rate variability.
RK Niemelä, SM Pikkujämsä, M Hakala… - The Journal of …, 2000 - europepmc.org
Objective Autonomic neuropathy is associated with increased mortality. In patients with
primary Sjögren's syndrome (SS), disturbances in the autonomic nervous system have been …
primary Sjögren's syndrome (SS), disturbances in the autonomic nervous system have been …
Does autonomic nervous impairment have a role in pathophysiology of Sjögren's syndrome
M Hakala, RK Niemelä - The Lancet, 2000 - thelancet.com
STI571 occupies the ATP pocket in the BCR-ABL kinase domain and substrates cannot be
phosphorylated. substrate for ABL kinase activity and, more importantly, the presumably …
phosphorylated. substrate for ABL kinase activity and, more importantly, the presumably …
[HTML][HTML] Association of accelerometer-measured physical activity, back static muscular endurance and abdominal obesity with radicular pain and non-specific low …
…, P Oura, J Takatalo, J Auvinen, K Raija, M Niemelä… - Scientific Reports, 2023 - nature.com
Low back pain (LBP) is the leading cause of disability worldwide and often associated with
lifestyle factors. However, studies further examining the role of these lifestyle factors in non-…
lifestyle factors. However, studies further examining the role of these lifestyle factors in non-…