C-reactive protein is postulated to embody an index that can reflect cardiovascular risk and
can be used to independently predict major cardiovascular events and mortality. On the other …

In recent years, it has become increasingly clear that arterial inflammation represents a key
feature determining the course of atherogenesis. The consecutive stages in the evolution of …

Background— Loss-of-function mutations in the ATP-binding cassette (ABCA)-1 gene locus
are the underlying cause for familial hypoalphalipoproteinemia, providing a human isolated …

C-reactive protein (CRP) has been postulated to play a causal part in atherosclerosis and
its acute complications. We assessed the effects of CRP-infusion on coagulation and …

Removal of cholesterol from peripheral tissues to the bloodstream via reverse cholesterol
transport (RCT) is a process of major biological importance. Here we demonstrate that …

Primary antiphospholipid syndrome (PAPS) is a systemic autoimmune disease characterized
by thrombosis, pregnancy morbidity, and the presence of antiphospholipid antibodies (aPL)…

Objectives : We investigated the consequences of an apolipoprotein AI (apoA-I) gene defect
with regard to lipid metabolism, endothelial function, arterial wall thickness, and coronary …

OBJECTIVES: Blocking the interleukin-6 pathway by tocilizumab (TCZ) has been associated
with changes in the lipoprotein profile, which could adversely impact cardiovascular (CV) …

Objective— Therapeutic interventions that increase plasma levels of high-density lipoproteins
and apolipoprotein AI (apoA-I) AI, the major high-density lipoprotein apolipoprotein, …

C-reactive protein (CRP) has been suggested to exert direct adverse effects on the vasculature
in experimental setups, including endothelial dysfunction and proinflammatory changes. …