[HTML][HTML] Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis

…, P Dolezalova, SM Garay, R Merino… - … England Journal of …, 2012 - Mass Medical Soc
Background Systemic juvenile idiopathic arthritis (JIA) is the most severe subtype of JIA;
treatment options are limited. Interleukin-6 plays a pathogenic role in systemic JIA. Methods We …

2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

…, D Maritsi, D McCurdy, R Merino… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop criteria for the classification of macrophage activation syndrome (MAS)
in patients with systemic juvenile idiopathic arthritis (JIA). Methods A multistep process, …

Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of …

…, P Miettunen, D Maritsi, R Merino… - Arthritis & …, 2014 - Wiley Online Library
Objective To describe the clinical, laboratory, and histopathologic features, current treatment,
and outcome of patients with macrophage activation syndrome (MAS) complicating …

High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: Results of an international multicenter …

…, J Frenkel, JI Aróstegui, J Yagüe, R Merino… - Arthritis & …, 2011 - Wiley Online Library
Objective Chronic infantile neurologic, cutaneous, articular (CINCA) syndrome, also known
as neonatal‐onset multisystem inflammatory disease (NOMID), is a dominantly inherited …

NOD2 gene–associated pediatric granulomatous arthritis: Clinical diversity, novel and recurrent mutations, and evidence of clinical improvement with interleukin‐1 …

JI Aróstegui, C Arnal, R Merino… - … : Official Journal of …, 2007 - Wiley Online Library
Objective Blau syndrome and early‐onset sarcoidosis are NOD2 gene–associated chronic
autoinflammatory diseases characterized by skin rash, arthritis, and/or eye involvement, with …

Blau syndrome: cross-sectional data from a multicentre study of clinical, radiological and functional outcomes

…, R Khubchandani, F Mackensen, R Merino… - …, 2015 - academic.oup.com
Objective. To report baseline articular, functional and ocular findings of the first international
prospective cohort study of Blau syndrome (BS). Methods. Three-year, multicentre, …

Clinical management algorithm of uveitis associated with juvenile idiopathic arthritis: interdisciplinary panel consensus

…, CG de Vicuña, V Hernández, R Merino… - Rheumatology …, 2015 - Springer
Uveitis associated with juvenile idiopathic arthritis (JIA) typically involves the anterior
chamber segment, follows an indolent chronic course, and presents a high rate of uveitic …

NOD2‐associated pediatric granulomatous arthritis, an expanding phenotype: study of an international registry and a national cohort in Spain

…, C Modesto, M Cristina Arnal, R Merino… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To study the phenotype characteristics of the largest to date cohort of patients with
pediatric granulomatous arthritis (PGA) and documented mutations in the NOD2 gene. …

Reduced joint assessment vs comprehensive assessment for ultrasound detection of synovitis in juvenile idiopathic arthritis

…, ML Gamir, I Calvo, ML García, R Merino… - …, 2013 - academic.oup.com
Objective. To propose a reduced joint power Doppler US (PDUS) assessment and provide
preliminary evidence of its validity, feasibility, reliability and sensitivity to change compared …

Blau syndrome–associated uveitis: preliminary results from an international prospective interventional case series

…, R Khubchandani, F Mackensen, R Merino… - American journal of …, 2018 - Elsevier
Purpose Provide baseline and preliminary follow-up results in a 5-year longitudinal study of
Blau syndrome. Design Multicenter, prospective interventional case series. Methods …