User profiles for ROBERT MURDOCH

Robert W. Murdoch

Battelle
Verified email at battelle.org
Cited by 647

A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization

…, AJ Watson, CS Law, ER Abraham, T Trull, R Murdoch… - Nature, 2000 - nature.com
Abstract Changes in iron supply to oceanic plankton are thought to have a significant effect
on concentrations of atmospheric carbon dioxide by altering rates of carbon sequestration, a …

Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial

S Khalid, R Murdoch, A Newlands, K Smart… - Journal of allergy and …, 2014 - Elsevier
Background Inhalation of capsaicin, the extract of hot chili peppers, induces coughing in both
animals and human subjects through activation of transient receptor potential vanilloid 1 (…

Formation of catechols via removal of acid side chains from ibuprofen and related aromatic acids

RW Murdoch, AG Hay - Applied and Environmental Microbiology, 2005 - Am Soc Microbiol
Although ibuprofen [2-(4-isobutylphenyl)-propionic acid] is one of the most widely consumed
drugs in the world, little is known regarding its degradation by environmental bacteria. …

Biodegradation of pharmaceutical and personal care products

J Kagle, AW Porter, RW Murdoch… - Advances in Applied …, 2009 - Elsevier
Medical treatments and personal hygiene lead to the steady release of pharmaceutical and
personal care products (PPCPs) into the environment. Some of these PPCPs have been …

Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2

RW Murdoch, AG Hay - Microbiology, 2013 - microbiologyresearch.org
Sphingomonas Ibu-2 has the unusual ability to cleave the acid side chain from the
pharmaceutical ibuprofen and related arylacetic acid derivatives to yield corresponding catechols …

The biotransformation of ibuprofen to trihydroxyibuprofen in activated sludge and by Variovorax Ibu-1

RW Murdoch, AG Hay - Biodegradation, 2015 - Springer
A bacterium was isolated from activated sewage sludge that has the ability to use ibuprofen
as its sole carbon and energy source. Phylogenetic analysis of the 16S rRNA gene …

Dehalogenation of Chlorinated Ethenes to Ethene by a Novel Isolate, “Candidatus Dehalogenimonas etheniformans”

…, F Kara Murdoch, Y Xie, RW Murdoch… - Applied and …, 2022 - Am Soc Microbiol
Dehalococcoides mccartyi strains harboring vinyl chloride (VC) reductive dehalogenase (RDase)
genes are keystone bacteria for VC detoxification in groundwater aquifers, and …

(Imidazo [1, 2-a] pyrimidin-2-yl) phenylmethanones and related compounds as potential nonsedative anxiolytics

…, CR Gardner, SS Matharu, R Murdoch… - Journal of medicinal …, 1988 - ACS Publications
Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine
receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo [l, 2-o] …

Metagenomes from Coastal Marine Sediments Give Insights into the Ecological Role and Cellular Features of Loki- and Thorarchaeota

L Manoharan, JA Kozlowski, RW Murdoch, FE Löffler… - MBio, 2019 - Am Soc Microbiol
The genomes of Asgard Archaea, a novel archaeal proposed superphylum, share an enriched
repertoire of eukaryotic signature genes and thus promise to provide insights into early …

Effects of a novel sodium channel blocker, GSK2339345, in patients with refractory chronic cough

…, S Siederer, L Liefaard, RD Murdoch… - … journal of clinical …, 2017 - search.proquest.com
Objective: Voltage-gated sodium channels (VGSC) are important in the initiation and propagation
of action potentials in afferent sensory nerve fibers responsible for evoking cough. This …