Objectives Although MRI data supports a link between spinal inflammation and formation of
new bone in ankylosing spondylitis, anti-tumour necrosis factor α therapies have not been …

Objective Fat metaplasia in bone marrow on T1‐weighted magnetic resonance imaging (MRI)
scans may develop after resolution of inflammation in patients with ankylosing spondylitis (…

Objective. There is an unmet need for reliable assessment of structural progression in the
sacroiliac joints (SIJ) of patients with spondyloarthritis (SpA), but radiography is unreliable and …

Magnetic resonance imaging (MRI) of the sacroiliac (SI) joints and the spine is increasingly
important in the assessment of inflammatory activity and structural damage in clinical trials …

Background Success of treatment withdrawal in patients with non-radiographic axial
spondyloarthritis who are in remission remains unknown. The ABILITY-3 study explored the ability …

Background MRI is frequently used for early diagnosis of axial spondyloarthritis (axSpA).
However, evaluation is time-consuming and requires profound expertise because …

OBJECTIVE: Infliximab, a neutralizing antibody to tumor necrosis factor-alpha, appears to
be effective therapy in ankylosing spondylitis (AS), although treatment is costly and serious …

Background: Involvement of the axial skeleton (sacroiliac joints and spine) is a relatively
frequent manifestation associated with psoriatic skin disease, mostly along with involvement of …

Objectives To determine quantitative SI joint MRI lesion cut-offs that optimally define a positive
MRI for inflammatory and structural lesions typical of axial SpA (axSpA) and that predict …

Background Studies have shown that structural lesions may be present in patients with non-radiographic
axial spondyloarthritis (nr-axSpA). However, the relevance of structural lesions …