COBRA combination therapy in patients with early rheumatoid arthritis: long‐term structural benefits of a brief intervention

…, M Boers, AC Verhoeven, R Westhovens… - Arthritis & …, 2002 - Wiley Online Library
Methods. All patients had participated in the 56-week COBRA trial. During followup, they were
seen by their own rheumatologists and were also assessed regularly by study nurses; no …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

…, T Stamm, T Takeuchi, R Westhovens… - Annals of the …, 2017 - ard.bmj.com
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international Task …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

…, T Takeuchi, M Voshaar, R Westhovens… - Annals of the …, 2020 - ard.bmj.com
Objectives To provide an update of the European League Against Rheumatism (EULAR)
rheumatoid arthritis (RA) management recommendations to account for the most recent …

[HTML][HTML] Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis

…, M Yanover, R Westhovens… - … England Journal of …, 1998 - Mass Medical Soc
Background Osteoporosis is a common complication of long-term glucocorticoid therapy for
which there is no well-proved preventive or restorative treatment. Methods We carried out …

Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis

…, HM Markusse, MAFJ van de Laar, R Westhovens… - The Lancet, 1997 - thelancet.com
Background The value of intensive combination therapy in early rheumatoid arthritis is
unproven. In a multicentre, double-blind, randomised trial (COBRA), we compared the …

[HTML][HTML] Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig

JM Kremer, R Westhovens, M Leon… - … England Journal of …, 2003 - Mass Medical Soc
Background Effective new therapies are needed for rheumatoid arthritis. Current therapies
target the products of activated macrophages; however, T cells also have an important role in …

Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial

…, T Li, Z Ge, JC Becker, R Westhovens - Annals of internal …, 2006 - acpjournals.org
Background: The selective co-stimulation modulator abatacept demonstrated efficacy for
treating rheumatoid arthritis in early clinical studies. Objective: To evaluate the effects of …

Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial

…, P Philippe, I Quéré, É Rich, R Westhovens… - Jama, 2014 - jamanetwork.com
Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

Two‐year effects of alendronate on bone mineral density and vertebral fracture in patients receiving glucocorticoids: a randomized, double‐blind, placebo‐controlled …

…, J Wing, HH McIlwain, R Westhovens… - … : Official Journal of …, 2001 - Wiley Online Library
Objective To evaluate the continued efficacy and safety of alendronate (ALN) for up to 2
years in patients receiving glucocorticoids. Methods This is a 12‐month extension of a …

EULAR evidence-based recommendations on the management of systemic glucocorticoid therapy in rheumatic diseases

…, KG Saag, B Svensson, R Westhovens… - Annals of the …, 2007 - ard.bmj.com
Objective: To develop evidence-based recommendations for the management of systemic
glucocorticoid (GC) therapy in rheumatic diseases. Methods: The multidisciplinary guideline …