Objective To evaluate the expression of type I interferon ( IFN α/β)– and type II IFN ( IFN γ)–inducible
genes in muscle biopsy specimens from patients with juvenile dermatomyositis ( …

Objective Sjögren syndrome in children is a poorly understood autoimmune disease. We
aimed to describe the clinical and diagnostic features of children diagnosed with Sjögren …

Objective. To assess anakinra as a therapy for systemic juvenile idiopathic arthritis (sJIA) in
a single-center series. Methods. We reviewed 25 patients with sJIA treated with anakinra for …

Background Data from routine clinical practice are needed to further define the efficacy and
safety of biologic medications in children with juvenile idiopathic arthritis (JIA). The aim of …

Objective. To evaluate safety, tolerability, and efficacy of etanercept in a cohort of patients
with juvenile idiopathic arthritis (JIA) under 4 years of age. Methods. Data were collected at …

Objective. To evaluate the rate of flare after etanercept (ETN) withdrawal in patients with
juvenile idiopathic arthritis (JIA) who attained clinical remission while taking medication, and to …

Background Pleural effusion in systemic lupus erythematous (SLE) is a common symptom,
and recent studies demonstrated that IL-6 has a pivotal role in its pathogenesis. Case …

Pansclerotic morphea (PSM) is a rare skin disease characterized by progressive stiffening
of the skin with or without the typical superficial skin changes usually seen in morphea (…

Objectives Paediatric Sjögren’s syndrome (pSS) is a rare chronic autoimmune disorder,
characterised by inflammation of exocrine glands. B cell hyperactivation plays a central role in …

Background Systemic juvenile idiopathic arthritis (sJIA) accounts for 10-20% of all patients
with JIA. The prominent systemic clinical features, the marked elevation of inflammatory …