Network analysis of associations between serum interferon‐α activity, autoantibodies, and clinical features in systemic lupus erythematosus

…, JA Kelly, M Kumabe, RA Mikolaitis… - Arthritis & …, 2011 - Wiley Online Library
Objective Interferon‐α (IFNα) is a primary pathogenic factor in systemic lupus erythematosus
(SLE), and high IFNα levels may be associated with particular clinical manifestations. The …

Disease-specific patient reported outcome tools for systemic lupus erythematosus

…, AS Pickard, JA Block, RB Kumar, RA Mikolaitis… - Seminars in arthritis and …, 2012 - Elsevier
PURPOSE: Systemic lupus erythematosus (SLE) can significantly affect both health and non-health-related
quality of life (HRQOL and non-HRQOL). However, of the existent published …

Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients

…, AA Kumar, M Badaracco, RA Mikolaitis… - The Journal of …, 2011 - journals.aai.org
Increased IFN-α signaling is a heritable risk factor for systemic lupus erythematosus (SLE).
IFN induced with helicase C domain 1 (IFIH1) is a cytoplasmic dsRNA sensor that activates …

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon‐α activity in lupus patients

…, SN Kariuki, L Rhee, RA Mikolaitis… - … : Official Journal of …, 2010 - Wiley Online Library
Objective Interferon‐α (IFNα) is a heritable risk factor for systemic lupus erythematosus (SLE).
Genetic variation near IRF7 is implicated in SLE susceptibility. SLE‐associated …

Lupus-specific health outcome measure for US patients: the LupusQoL-US version

M Jolly, AS Pickard, C Wilke, RA Mikolaitis… - Annals of the …, 2010 - ard.bmj.com
Background: Patient-reported outcomes are valuable for the management of chronic diseases
like systematic lupus erythematosus (SLE), but no measures have been validated for use …

[HTML][HTML] Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus …

…, AA Kumar, J Arrington, RA Mikolaitis… - Arthritis research & …, 2010 - Springer
Introduction Systemic lupus erythematosus (SLE) is a highly heterogeneous disorder,
characterized by differences in autoantibody profile, serum cytokines, and clinical manifestations. …

Serum free light chains as biomarkers for systemic lupus erythematosus disease activity

…, W Sequeira, R Kokebie, RA Mikolaitis… - Arthritis care & …, 2011 - Wiley Online Library
Objective To evaluate serum free light chains (FLC) as a putative biomarker of systemic lupus
erythematosus (SLE) activity. Methods Seventy‐five SLE patients and 41 age‐ and sex‐…

Psychometric properties of the EuroQol-5D and Short Form-6D in patients with systemic lupus erythematosus

…, CT Wilke, AS Pickard, V Vats, R Mikolaitis… - The Journal of …, 2009 - jrheum.org
Objective. Health related quality of life (HRQOL) is an important patient-reported outcome in
systemic lupus erythematosus (SLE). We evaluated the psychometric properties of 2 widely …

Body image in patients with systemic lupus erythematosus

M Jolly, AS Pickard, RA Mikolaitis, J Cornejo… - International journal of …, 2012 - Springer
Background Systemic lupus erythematosus (SLE), a multisystemic disease of young women
may be disfiguring and affect physical and emotional health. Body image literature in SLE is …

Improvement in knee loading after use of specialized footwear for knee osteoarthritis: results of a six‐month pilot investigation

…, RH Lidtke, MA Wimmer, RA Mikolaitis… - Arthritis & …, 2013 - Wiley Online Library
Objective Biomechanical interventions for knee osteoarthritis (OA) aim to improve pain and
retard disease progression by decreasing knee loading. This study was undertaken to …