Clinical management algorithm of uveitis associated with juvenile idiopathic arthritis: interdisciplinary panel consensus

…, CG de Vicuña, V Hernández, R Merino… - Rheumatology …, 2015 - Springer
Uveitis associated with juvenile idiopathic arthritis (JIA) typically involves the anterior
chamber segment, follows an indolent chronic course, and presents a high rate of uveitic …

[HTML][HTML] Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis

…, SM Garay, R Merino, R Joos… - … England Journal of …, 2012 - Mass Medical Soc
Background Systemic juvenile idiopathic arthritis (JIA) is the most severe subtype of JIA;
treatment options are limited. Interleukin-6 plays a pathogenic role in systemic JIA. Methods We …

2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

…, D Maritsi, D McCurdy, R Merino… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop criteria for the classification of macrophage activation syndrome (MAS)
in patients with systemic juvenile idiopathic arthritis (JIA). Methods A multistep process, …

Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of …

…, P Miettunen, D Maritsi, R Merino… - Arthritis & …, 2014 - Wiley Online Library
Objective To describe the clinical, laboratory, and histopathologic features, current treatment,
and outcome of patients with macrophage activation syndrome (MAS) complicating …

The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb

R Merino, J Rodriguez-Leon, D Macias… - …, 1999 - journals.biologists.com
In this study, we have analyzed the expression and function of Gremlin in the developing
avian limb. Gremlin is a member of the DAN family of BMP antagonists highly conserved …

The phenotype of TNF receptor-associated autoinflammatory syndrome (TRAPS) at presentation: a series of 158 cases from the Eurofever/EUROTRAPS international …

…, R Merino, C Modesto, N Toplak, R Berendes… - Annals of the …, 2014 - ard.bmj.com
Objective To evaluate the genetic findings, demographic features and clinical presentation
of tumour necrosis factor receptor-associated autoinflammatory syndrome (TRAPS) in …

High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: Results of an international multicenter …

…, J Frenkel, JI Aróstegui, J Yagüe, R Merino… - Arthritis & …, 2011 - Wiley Online Library
Objective Chronic infantile neurologic, cutaneous, articular (CINCA) syndrome, also known
as neonatal‐onset multisystem inflammatory disease (NOMID), is a dominantly inherited …

[PDF][PDF] Consensus document on treatment of infections in diabetic foot

JI Blanes, R Merino, F Lozano, JG del Castillo… - Rev Esp …, 2011 - researchgate.net
Diabetic foot infection, particularly if it is associated to ischaemia, is the most common cause
of lower limb amputation, in the general population, of hospital admissions, and a decrease …

[HTML][HTML] Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: Sox genes and BMP signaling

…, JA Montero, Y Ganan, D Macias, R Merino… - Developmental …, 2003 - Elsevier
Here, we have studied how Sox genes and BMP signaling are functionally coupled during
limb chondrogenesis. Using the experimental model of TGFβ1-induced interdigital digits, we …

Developmental regulation of the Bcl‐2 protein and susceptibility to cell death in B lymphocytes.

R Merino, L Ding, DJ Veis, SJ Korsmeyer… - The EMBO …, 1994 - embopress.org
Cell death is a prominent feature of B cell development. For example, a large population of
B cells dies at the pre‐B cell stage presumably due to the failure to express a functional …