To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide
association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 …

The objective of this study was to investigate the expression of IL-23 and IL-17 and the
influence of IL-23 on IL-17 production in ankylosing spondylitis (AS) patients. IL-23 and IL-17 …

MicroRNAs (miRNAs) play a key role in the regulation of almost all the physiological and
pathological processes, including bone metabolism. Recent studies have suggested that miR-…

Background Dyslipidemia often concurs with hyperuricemia. Our study was to discover
different lipid levels of gout and asymptomatic hyperuricemia and the predictors of sUA (serum …

Growing evidence suggests that the gut microbiota is involved in the initiation and progression
of ankylosing spondylitis (AS). In this study, we aimed to explore the gut microbiome …

Background Microbial involvement in ankylosing spondylitis (AS) has been suggested; however,
the relationship between gut microbiome and the disease phenotypes of AS remains to …

Objectives Our study objective was to explore whether abnormalities in the subtypes of T
cells and B cells were present in peripheral blood of patients with osteoarthritis (OA) and …

Our aim was to investigate the prevalence of psychological disorders, sleep disturbance,
and stressful life events in Chinese patients with ankylosing spondylitis (AS) and healthy …

Macrophages play a critical role in ankylosing spondylitis by promoting autoimmune tissue
inflammation through various effector functions. The inflammatory potential of macrophages …

Ankylosing spondylitis (AS) is a type of spondyloarthropathies, the diagnosis of which is often
delayed. The lack of early diagnosis tools often delays the institution of appropriate therapy…