Objectives. Although clinicians recognize hip involvement, which frequently leads to hip
replacement surgery, as an important feature of AS, data on the epidemiology, nature of the …

Introduction The advent of anti-tumor necrosis factor alpha (anti-TNFα) drugs has considerably
improved medical management in rheumatoid arthritis (RA) patients, although it has been …

Objective To assess HLA-B27 influence on the clinical phenotype of Ankylosing Spondylitis (AS)
patients. Method An observational, cross-sectional and descriptive study of AS patients …

Tocilizumab (TCZ) is an effective treatment for rheumatoid arthritis (RA). However, the changes
that occurred after TCZ therapy on endothelial dysfunction, monocyte activity, NETosis, …

Objective. To determine the first signs and symptoms, and the clinical, biological and
radiological characteristics of patients with early SpA. Methods. A total of 150 SpA patients were …

Objective: Systemic lupus erythematosus (SLE) is associated to boosted atherosclerosis
development and a higher cardiovascular disease risk. This study aimed to delineate the role of …

Objective. To compare the clinical, demographic, and serologic characteristics and the
treatment of patients diagnosed with ankylosing spondylitis (AS) from Europe (EU) and Latin …

Background Plasma concentrations of lipoprotein (a) (Lp(a)), a lipoprotein with atherogenic
and thrombogenic properties, have a strong genetic basis, although high concentrations of …

Objectives To characterise splicing machinery (SM) alterations in leucocytes of patients with
rheumatoid arthritis (RA), and to assess its influence on their clinical profile and therapeutic …

Objective. Ankylosing spondylitis (AS) is generally observed in young patients but can occur
later in life or in persons ≥ 50 years of age. Our objective was to characterize the clinical …