Markers of inflammation are negatively correlated with serum leptin in rheumatoid arthritis
…, PL van Riel, P Barrera, JWM van der Meer - Annals of the …, 2005 - ard.bmj.com
Background: Leptin regulates food intake and modulates immunity and inflammation. A
positive feedback mechanism has been described between tumour necrosis factor (TNF) and …
positive feedback mechanism has been described between tumour necrosis factor (TNF) and …
Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade
…, MI Koenders, PL van Riel, FA van de Loo… - Annals of the …, 2011 - ard.bmj.com
Objective To investigate the interplay between IL-32 and tumour necrosis factor alpha (TNFα)
during the chronic inflammation of rheumatoid arthritis (RA) and to assess whether anti-…
during the chronic inflammation of rheumatoid arthritis (RA) and to assess whether anti-…
Down-titration and discontinuation of infliximab in rheumatoid arthritis patients with stable low disease activity and stable treatment: an observational cohort study
…, FHJ van den Hoogen, PL van Riel… - Annals of the …, 2012 - ard.bmj.com
Down-titration, or discontinuing infliximab, has proven to be feasible in RA patients. Therefore,
our local treatment protocol includes tapering infliximab dose. This observational study …
our local treatment protocol includes tapering infliximab dose. This observational study …
Increased fascial thickness of the deltoid muscle in dermatomyositis and polymyositis: an ultrasound study
Introduction: We investigated the use of ultrasound to detect fascial thickening of the deltoid,
vastus lateralis (VL), and rectus femoris (RF) muscles in dermatomyositis (DM) and …
vastus lateralis (VL), and rectus femoris (RF) muscles in dermatomyositis (DM) and …
Should we redefine treatment targets in rheumatoid arthritis? Low disease activity is sufficiently strict for patients who are anticitrullinated protein antibody-negative
…, AA den Broeder, EV Pascual, PL van Riel… - The Journal of …, 2013 - jrheum.org
Objective. Clinical remission currently is the treatment target for all patients with rheumatoid
arthritis (RA). At the same level of inflammation, the prognosis regarding joint damage is …
arthritis (RA). At the same level of inflammation, the prognosis regarding joint damage is …
[HTML][HTML] IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis
…, S Holewijn, J de Graaf, JC Dos Santos, PL van Riel… - Scientific reports, 2017 - nature.com
Patients with rheumatoid arthritis (RA) are at higher risk of developing cardiovascular diseases
(CVD). Interleukin (IL)-32 has previously been shown to be involved in the pathogenesis …
(CVD). Interleukin (IL)-32 has previously been shown to be involved in the pathogenesis …
[HTML][HTML] Functional consequences of DECTIN-1early stop codon polymorphism Y238X in rheumatoid arthritis
…, R Stienstra, PL van Riel, WB van den Berg… - Arthritis research & …, 2010 - Springer
Introduction Dectin-1, a pattern recognition receptor expressed by the innate immune system,
is known to be a major receptor inducing Th17-type adaptive immune responses that have …
is known to be a major receptor inducing Th17-type adaptive immune responses that have …
Cytokine production of stimulated whole blood cultures in rheumatoid arthritis patients receiving short-term infliximab therapy
…, PL van Riel, BJ Kullberg, JWM Van der Meer - Cytokine, 2005 - Elsevier
Patients with rheumatoid arthritis (RA) treated with anti-tumor necrosis factor (TNF) strategies
have an increased susceptibility to infections, especially those caused by intracellular …
have an increased susceptibility to infections, especially those caused by intracellular …
Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis
…, AHM van der Helm-van Mil, WB van den Berg… - …, 2013 - academic.oup.com
Objective. One of the disease hallmarks of RA is progressive cartilage and bone destruction
in the joints. The exact mechanism underlying this disease process is largely unknown. …
in the joints. The exact mechanism underlying this disease process is largely unknown. …
Risk factors of second-line antirheumatic drugs in rheumatoid arthritis
…, PL van Riel, FW Gribnau, LB van de Putt - Seminars in arthritis and …, 1990 - Elsevier
D RUGS PLAY an important role in the treatment of patients with rheumatoid arthritis (RA).
Unlike nonsteroidal antiinllammatory drugs (NSAIDs), disease modifying antirheumatic drugs (…
Unlike nonsteroidal antiinllammatory drugs (NSAIDs), disease modifying antirheumatic drugs (…