Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community
…, PJW Venables, MJ Wattiaux, P Youinou - … : Official Journal of …, 1993 - Wiley Online Library
Objective. Different sets of diagnostic criteria have been proposed for Sjögren's syndrome (SS),
but none have been validated with a large series of patients or in a multicenter study. We …
but none have been validated with a large series of patients or in a multicenter study. We …
The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease characterized by a distinctive
pattern of bone and joint destruction. RA patients have an increased risk of death. The …
pattern of bone and joint destruction. RA patients have an increased risk of death. The …
BAFF overexpression is associated with autoantibody production in autoimmune diseases
The B‐cell activity factor (BAFF) acts as a positive regulator of B‐cell function. To gain further
insight into the understanding of B‐cell hyperactivity in autoimmune diseases, the serum …
insight into the understanding of B‐cell hyperactivity in autoimmune diseases, the serum …
Improvement of Sjögren's syndrome after two infusions of rituximab (anti‐CD20)
…, IQ Roué, B Cochener, P Youinou… - Arthritis care & …, 2007 - Wiley Online Library
Objective. There is evidence to support a dominant role for B cells in the pathophysiology of
primary Sjögren's syndrome
primary Sjögren's syndrome
Epigenetics and autoimmunity
WH Brooks, C Le Dantec, JO Pers, P Youinou… - Journal of …, 2010 - Elsevier
Advances in genetics, such as sequencing of the human genome, have contributed to
identification of susceptible genetic patterns in autoimmune diseases (AID). However, genetics is …
identification of susceptible genetic patterns in autoimmune diseases (AID). However, genetics is …
Contribution of salivary gland ultrasonography to the diagnosis of Sjögren's syndrome: toward new diagnostic criteria?
…, S Boisramé‐Gastrin, E Nowak, P Youinou… - Arthritis & …, 2013 - Wiley Online Library
Objective To determine the accuracy of salivary gland ultrasonography (SGUS) for
diagnosing primary Sjögren's syndrome (SS) and to suggest modifications of the American–European …
diagnosing primary Sjögren's syndrome (SS) and to suggest modifications of the American–European …
Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome
Objective. To identify the cells that produce BAFF in the salivary glands of patients with
primary Sjögren’s syndrome (SS), and to analyze BAFF receptor expression by local T and B …
primary Sjögren’s syndrome (SS), and to analyze BAFF receptor expression by local T and B …
Ability of the American College of Rheumatology 1987 criteria to predict rheumatoid arthritis in patients with early arthritis and classification of these patients two years …
…, E Botton, JY Mary, P Le Goff, P Youinou - Arthritis & …, 2001 - Wiley Online Library
Objective To determine how well the American College of Rheumatology (ACR; formerly,
the American Rheumatism Association) 1987 classification criteria for rheumatoid arthritis (RA), …
the American Rheumatism Association) 1987 classification criteria for rheumatoid arthritis (RA), …
Anti–TNF‐α immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis
…, A Saraux, R Pierre, P Youinou - Journal of …, 2008 - Wiley Online Library
Background: Because periodontitis presents many similarities with rheumatoid arthritis (RA)
with regard to tumor necrosis factor‐alpha (TNF‐α)‐induced bone resorption, the benefits of …
with regard to tumor necrosis factor‐alpha (TNF‐α)‐induced bone resorption, the benefits of …
The binding of some human antiendothelial cell antibodies induces endothelial cell apoptosis.
…, JC Piette, Y Shoenfeld, PY Youinou - The Journal of …, 1998 - Am Soc Clin Investig
… Youinou, manuscript submitted for publication). Studies are in progress to identify the cell
surface epitope(s) that apoptosis-inducing AECA recognize. Further analysis of human …
surface epitope(s) that apoptosis-inducing AECA recognize. Further analysis of human …