A bio-physically inspired silicon neuron

E Farquhar, P Hasler - … Transactions on Circuits and Systems I …, 2005 - ieeexplore.ieee.org
The physical principles governing ion flow in biological neurons share interesting similarities
to electron flow through the channels of MOSFET transistors. Here, is described a circuit …

A single-transistor silicon synapse

C Diorio, P Hasler, A Minch… - IEEE transactions on …, 1996 - ieeexplore.ieee.org
We have developed a new floating-gate silicon MOS transistor for analog learning applications.
The memory storage is nonvolatile; hot-electron injection and electron tunneling permit …

Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia

AK Gupta, P Hasler, W Holzgreve, S Gebhardt… - Human immunology, 2005 - Elsevier
Preeclampsia, a severe pregnancy-related disorder, involves an overt activation of the
maternal innate immune system, proposed to result from the elevated release of inflammatory …

A digitally enhanced dynamically reconfigurable analog platform for low-power signal processing

…, S Shapero, S Nease, P Hasler - IEEE Journal of Solid …, 2012 - ieeexplore.ieee.org
We present a field-programmable analog array designed for accurate low-power mixed-signal
computation. This 25-mm 2 350 nm-CMOS reconfigurable analog IC incorporates digital …

Large-scale field-programmable analog arrays for analog signal processing

TS Hall, CM Twigg, JD Gray, P Hasler… - IEEE Transactions on …, 2005 - ieeexplore.ieee.org
Field-programmable analog arrays (FPAAs) provide a method for rapidly prototyping analog
systems. Currently available commercial and academic FPAAs are typically based on …

A CMOS programmable analog memory-cell array using floating-gate circuits

RR Harrison, JA Bragg, P Hasler… - … on Circuits and …, 2001 - ieeexplore.ieee.org
The complexity of analog VLSI systems is often limited by the number of pins on a chip
rather than by the die area. Currently, many analog parameters and biases are stored off-chip. …

[HTML][HTML] Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

AK Gupta, MB Joshi, M Philippova, P Erne, P Hasler… - FEBS letters, 2010 - Elsevier
Neutrophil interaction with activated endothelial cells (EC) is required for transmigration. We
examined consequences of this interaction on NETosis. Co-culture of activated EC with …

A learning-enabled neuron array IC based upon transistor channel models of biological phenomena

S Brink, S Nease, P Hasler… - … Circuits and Systems, 2012 - ieeexplore.ieee.org
We present a single-chip array of 100 biologically-based electronic neuron models interconnected
to each other and the outside environment through 30,000 synapses. The chip was …

[HTML][HTML] Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility

…, UA Walker, A Buser, S Hahn, P Hasler - Arthritis research & …, 2014 - Springer
Introduction Neutrophil extracellular traps (NETs) have recently been implicated in a number
of autoimmune conditions, including rheumatoid arthritis (RA). We examined the underlying …

[HTML][HTML] Efficient neutrophil extracellular trap induction requires mobilization of both intracellular and extracellular calcium pools and is modulated by cyclosporine A

AK Gupta, S Giaglis, P Hasler, S Hahn - PloS one, 2014 - journals.plos.org
Excessive or aberrant generation of neutrophil extracellular traps (NETs) has recently
become implicated in the underlying aetiology of a number of human pathologies including …