The type I interferon system is integral to human antiviral immunity. However, inappropriate
stimulation or defective negative regulation of this system can lead to inflammatory disease. …

Objectives To analyse the prevalence of CECR1 mutations in patients diagnosed with early
onset livedo reticularis and/or haemorrhagic/ischaemic strokes in the context of inflammation …

Familial Mediterranean fever (FMF) and Behçet's disease (BD), both inflammatory diseases,
are highly prevalent in the Middle Eastern and Mediterranean populations. FMF is a …

Microbial nucleic acid recognition serves as the major stimulus to an antiviral response,
implying a requirement to limit the misrepresentation of self nucleic acids as non-self and the …

Primary Sjögren syndrome (SS) is very rare in childhood. We collected a series of primary
paediatric SS cases from different centres. A data collection form was prepared and sent to …

Objective Osteopenia/osteoporosis is being increasingly reported as a complication of many
chronic diseases, even in children. In this preliminary study, we evaluated the effect of an …

The life-threatening Immunodeficiency, Centromeric Instability and Facial Anomalies (ICF)
syndrome is a genetically heterogeneous autosomal recessive disorder. Twenty percent of …

Recurrent pericarditis occurs in association with various medical conditions, but in most
cases the condition appears to be idiopathic. Although high‐dose steroid treatment is often …

Objective To explore tumor necrosis factor (TNF)–induced apoptosis in neutrophils from
patients with TNF receptor–associated periodic syndrome (TRAPS) and to correlate the results …

Objective To compare whole-body MRI (WB-MRI) with clinical examination in the assessment
of disease activity in juvenile dermatomyositis (JDM). Methods WB-MR images were …