User profiles for PETER GARRED
 | Peter GarredProfessor of Clinical Molecular Medicine, University of Copenhagen Verified email at post5.tele.dk Cited by 27793 |
Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein.
Mannan-binding protein (MBP) is a serum lectin participating in the innate immune defense
by opsonizing various microorganisms for phagocytosis. Opsonization defect due to MBP …
by opsonizing various microorganisms for phagocytosis. Opsonization defect due to MBP …
Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride: a meta-analysis
NA Graudal, AM Galløe, P Garred - Jama, 1998 - jamanetwork.com
Context.—One of the controversies in preventive medicine is whether a general reduction in
sodium intake can decrease the blood pressure of a population and thereby reduce the …
sodium intake can decrease the blood pressure of a population and thereby reduce the …
[HTML][HTML] Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
P Garred, T Pressler, HO Madsen… - The Journal of …, 1999 - Am Soc Clin Investig
Mannose-binding lectin (MBL) is a key factor in innate immunity, and lung infections are the
leading cause of morbidity and mortality in cystic fibrosis (CF). Accordingly, we investigated …
leading cause of morbidity and mortality in cystic fibrosis (CF). Accordingly, we investigated …
Acute respiratory tract infections and mannose-binding lectin insufficiency during early childhood
…, CH Hansen, LH Andersen, GW Hahn, P Garred - Jama, 2001 - jamanetwork.com
ContextHospital-based studies have found that increased susceptibility to certain infections
is associated with low serum levels of mannose-binding lectin (MBL) due to MBL variant …
is associated with low serum levels of mannose-binding lectin (MBL) due to MBL variant …
Mannose-binding lectin deficiency—revisited
P Garred, F Larsen, HO Madsen, C Koch - Molecular immunology, 2003 - Elsevier
There is an emerging interest for mannose-binding lectin (MBL) due to its role in innate
immunity. In this survey we present a mixture of old and new data describing the effect MBL …
immunity. In this survey we present a mixture of old and new data describing the effect MBL …
[HTML][HTML] Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
…, H Bundgaard, SD Nielsen, P Garred - Nature …, 2022 - nature.com
SARS-CoV-2 vaccines are crucial in controlling COVID-19, but knowledge of which factors
determine waning immunity is limited. We examined antibody levels and T-cell gamma-…
determine waning immunity is limited. We examined antibody levels and T-cell gamma-…
Mannose-binding lectin and its genetic variants
Mannose-binding lectin (MBL) is a collagen-like serum protein that mediates activation of the
complement system and is of importance for host defence. Common variant alleles situated …
complement system and is of importance for host defence. Common variant alleles situated …
Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America
…, ML Satz, B Hogh, A Svejgaard, P Garred - The Journal of …, 1998 - journals.aai.org
Previous studies have shown that three point mutations in exon 1 and a particular promoter
haplotype of the mannan-binding lectin (MBL) gene lead to a dramatic decrease in the …
haplotype of the mannan-binding lectin (MBL) gene lead to a dramatic decrease in the …
Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin
P Garred, HO Madsen, U Balslev, BO Hofmann… - The Lancet, 1997 - thelancet.com
Background Low serum concentrations of mannose-binding lectin (MBL) are associated with
increased susceptibility to recurrent infection. Three variant alleles in the MBL gene (B, C, …
increased susceptibility to recurrent infection. Three variant alleles in the MBL gene (B, C, …
Mannose‐binding lectin engagement with late apoptotic and necrotic cells
The serum opsonin mannose‐binding lectin (MBL) has been shown to be involved in the
handling of apoptotic cells. However, at what stage in the process this happens and whether …
handling of apoptotic cells. However, at what stage in the process this happens and whether …