An improved approach for construction of bacterial artificial chromosome libraries
K Osoegawa, PY Woon, B Zhao, E Frengen, M Tateno… - Genomics, 1998 - Elsevier
Presented here are improved methodologies that enable the generation of highly redundant
bacterial artificial chromosome/P1-derived artificial chromosome libraries, with larger and …
bacterial artificial chromosome/P1-derived artificial chromosome libraries, with larger and …
Bacterial artificial chromosome libraries for mouse sequencing and functional analysis
K Osoegawa, M Tateno, PY Woon, E Frengen… - Genome …, 2000 - genome.cshlp.org
Bacterial artificial chromosome (BAC) and P1-derived artificial chromosome (PAC) libraries
providing a combined 33-fold representation of the murine genome have been constructed …
providing a combined 33-fold representation of the murine genome have been constructed …
[HTML][HTML] ITPKC Single Nucleotide Polymorphism Associated with the Kawasaki Disease in a Taiwanese Population
…, YS Wang, CH Lee, E Hsi, HR Yu, PY Woon… - PloS one, 2011 - journals.plos.org
Kawasaki disease (KD) is characterized by systemic vasculitis with unknown etiology.
Previous studies from Japan indicated that a gene polymorphism of ITPKC (rs28493229) is …
Previous studies from Japan indicated that a gene polymorphism of ITPKC (rs28493229) is …
[HTML][HTML] Increased risk of atopic dermatitis in preschool children with Kawasaki disease: a population-based study in Taiwan
PY Woon, WC Chang, CC Liang, CH Hsu… - Evidence-Based …, 2013 - hindawi.com
Kawasaki disease (KD) is an acute febrile systemic vasculitis and has been reported to be
associated with allergic disease. The risk of atopic dermatitis (AD) in preschool children with …
associated with allergic disease. The risk of atopic dermatitis (AD) in preschool children with …
[HTML][HTML] Targeting PSEN1 by lnc-CYP3A43-2/miR-29b-2-5p to Reduce β Amyloid Plaque Formation and Improve Cognition Function
…, SP Chen, BA Tannous, WS Huang, PY Woon… - International Journal of …, 2022 - mdpi.com
Presenilin-1 (PSEN1) is a crucial subunit within the γ-secretase complex and regulates β-amyloid
(Aβ) production. Accumulated evidence indicates that n-butylidenephthalide (BP) acts …
(Aβ) production. Accumulated evidence indicates that n-butylidenephthalide (BP) acts …
[HTML][HTML] The Prevalence of TET2 Gene Mutations in Patients with BCR-ABL-Negative Myeloproliferative Neoplasms (MPN): A Systematic Review and Meta-Analysis
Simple Summary Many molecular biology techniques have been widely used to study the
pathogenesis of different diseases, particularly haematologic malignancies which are …
pathogenesis of different diseases, particularly haematologic malignancies which are …
R450H TSH receptor mutation in congenital hypothyroidism in Taiwanese children
…, WC Chen, YC Fan, SJ Chiu, HC Kuo, PY Woon… - Clinica chimica acta, 2012 - Elsevier
BACKGROUND: The most common congenital endocrine disorder, congenital hypothyroidism
(CHT), is strongly associated with thyroid hormone deficiency. Previous studies have …
(CHT), is strongly associated with thyroid hormone deficiency. Previous studies have …
[HTML][HTML] A Genetic Polymorphism (rs17251221) in the Calcium-Sensing Receptor Gene (CASR) Is Associated with Stone Multiplicity in Calcium Nephrolithiasis
YH Chou, PY Woon, WC Chen, YW Hsu, JM Chang… - PLoS …, 2011 - journals.plos.org
Calcium nephrolithiasis is one of the most common causes of renal stones. While the prevalence
of this disease has increased steadily over the last 3 decades, its pathogenesis is still …
of this disease has increased steadily over the last 3 decades, its pathogenesis is still …
[HTML][HTML] FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease
HC Kuo, YW Hsu, MS Wu, PY Woon… - Mediators of …, 2015 - hindawi.com
Kawasaki disease (KD) is characterized by pediatric systemic vasculitis of an unknown
cause. The low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) gene was …
cause. The low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) gene was …
Construction and characterization of a 10-fold genome equivalent rat P1-derived artificial chromosome library
PY Woon, K Osoegawa, PJ Kaisaki, B Zhao… - Genomics, 1998 - Elsevier
A rat PAC library was constructed in the vector pPAC4 from genomic DNA isolated from
female Brown Norway rats. This library consists of 215,409 clones arrayed in 614 384-well …
female Brown Norway rats. This library consists of 215,409 clones arrayed in 614 384-well …