Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress
P Decker, S Muller - Current pharmaceutical biotechnology, 2002 - ingentaconnect.com
Poly (ADP-ribose) polymerase is a zinc-finger DNA-binding enzyme which detects and signals
DNA strand breaks generated either directly during base excision repair, or indirectly by …
DNA strand breaks generated either directly during base excision repair, or indirectly by …
Photobodies in light signaling
EK Van Buskirk, PV Decker, M Chen - Plant physiology, 2012 - academic.oup.com
Plant development and growth are extremely plastic in response to changes in ambient light
conditions. Light is not only the ultimate energy source for photosynthesis; its physical …
conditions. Light is not only the ultimate energy source for photosynthesis; its physical …
[HTML][HTML] Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors
…, AM Molinaro, KM Walsh, PA Decker… - … England Journal of …, 2015 - Mass Medical Soc
Background The prediction of clinical behavior, response to therapy, and outcome of infiltrative
glioma is challenging. On the basis of previous studies of tumor biology, we defined five …
glioma is challenging. On the basis of previous studies of tumor biology, we defined five …
JAK inhibitors and systemic sclerosis: A systematic review of the literature
C Moriana, T Moulinet, R Jaussaud, P Decker - Autoimmunity reviews, 2022 - Elsevier
… The alpha risk was 5% (p-value of <0.05 was considered significant). … 54 months [IQR:
42–78] in the late SSc group (p < 0.0001). “Early” SSc patients were significantly younger at the …
42–78] in the late SSc group (p < 0.0001). “Early” SSc patients were significantly younger at the …
[HTML][HTML] PARP-2, A novel mammalian DNA damage-dependent poly (ADP-ribose) polymerase
…, V Schreiber, C Niedergang, F Apiou, P Decker… - Journal of Biological …, 1999 - ASBMB
Poly(ADP-ribosylation) is a post-translational modification of nuclear proteins in response to
DNA damage that activates the base excision repair machinery. Poly(ADP-ribose) …
DNA damage that activates the base excision repair machinery. Poly(ADP-ribose) …
[HTML][HTML] Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than …
GE Darling, MS Allen, PA Decker, K Ballman… - The Journal of thoracic …, 2011 - Elsevier
… The median survival is 8.1 years for mediastinal lymph node sampling and 8.5 years for
mediastinal lymph node dissection (P = .25). The 5-year disease-free survival was 69% (95% …
mediastinal lymph node dissection (P = .25). The 5-year disease-free survival was 69% (95% …
Polymyositis–dermatomyositis-associated interstitial lung disease
…, TE Hartman, RP Hartman, PA Decker… - American journal of …, 2001 - atsjournals.org
We report findings in 70 patients with both diffuse interstitial lung disease and either
polymyositis (PM) or dermatomyositis (DM). Initial presentations were most commonly either …
polymyositis (PM) or dermatomyositis (DM). Initial presentations were most commonly either …
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
…, RB Jenkins, JS Chang, RF Yeh, Y Xiao, PA Decker… - Nature …, 2009 - nature.com
The causes of glioblastoma and other gliomas remain obscure 1 , 2 . To discover new
candidate genes influencing glioma susceptibility, we conducted a principal component–adjusted …
candidate genes influencing glioma susceptibility, we conducted a principal component–adjusted …
[HTML][HTML] Resistance to endotoxic shock as a consequence of defective NF‐κB activation in poly (ADP‐ribose) polymerase‐1 deficient mice
…, J Ménissier‐de Murcia, C Nacci, P Decker… - The EMBO …, 1999 - embopress.org
Poly (ADP‐ribose) polymerase‐1 is a nuclear DNA‐binding protein that participates in the
DNA base excision repair pathway in response to genotoxic stress in mammalian cells. Here …
DNA base excision repair pathway in response to genotoxic stress in mammalian cells. Here …
Cigarette smoking is strongly associated with mutation of the K‐ras gene in patients with primary adenocarcinoma of the lung
SA Ahrendt, PA Decker, EA Alawi, Y Zhu… - Cancer, 2001 - Wiley Online Library
BACKGROUND The majority of lung carcinoma cases occur in current or former smokers. K‐ras
gene mutations are common in lung adenocarcinoma and have been associated with …
gene mutations are common in lung adenocarcinoma and have been associated with …