[HTML][HTML] Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC)-the hot start experience

…, J Dewender, S Reimann, G Stacey, O O'shea… - Stem Cell Research, 2017 - Elsevier
A fast track “Hot Start” process was implemented to launch the European Bank for Induced
Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and …

Report of the international stem cell banking initiative workshop activity: current hurdles and progress in seed-stock banking of human pluripotent stem cells

…, M Sheldon, N Rahman, O O'Shea… - Stem cells …, 2017 - academic.oup.com
This article summarizes the recent activity of the International Stem Cell Banking Initiative (ISCBI)
held at the California Institute for Regenerative Medicine (CIRM) in California (June 26, …

[HTML][HTML] Development and implementation of large-scale quality control for the European bank for induced Pluripotent Stem Cells

O O'Shea, R Steeg, C Chapman, P Mackintosh… - Stem cell …, 2020 - Elsevier
The European Bank for induced Pluripotent Stem Cells (EBiSC) has collected iPSC lines
associated with genetic diseases and healthy controls from across Europe and made these …

[HTML][HTML] Curcumin inhibits prostate cancer bone metastasis by up-regulating bone morphogenic protein-7 in vivo

T Dorai, J Diouri, O O'Shea, SB Doty - Journal of cancer therapy, 2014 - ncbi.nlm.nih.gov
A number of studies have focused on the beneficial properties of Curcumin (diferuloyl methane,
used in South Asian cuisine and traditional medicine) such as the chemoprevention of …

Report of the international conference on manufacturing and testing of pluripotent stem cells

…, S Lin, S Lin-Gibson, A Lubiniecki, O O'Shea… - Biologicals, 2018 - Elsevier
Sessions included an overview of past cell therapy (CT) conferences sponsored by the
International Alliance for Biological Standardization (IABS). The sessions highlighted challenges …

Mammalian target of rapamycin pathway assessment in antiphospholipid antibody–positive patients with livedo

…, WD Shipman, O O'Shea, J Harp, O Alpan… - The Journal of …, 2022 - jrheum.org
Objective In antiphospholipid antibody (aPL) nephropathy, activation of the mammalian
target of rapamycin (mTOR) contributes to endothelial cell proliferation, a key finding of aPL …

Nisin H is a new nisin variant produced by the gut-derived strain Streptococcus hyointestinalis DPC6484

…, EF O'Shea, CM Guinane, O O'Sullivan… - Applied and …, 2015 - Am Soc Microbiol
Accumulating evidence suggests that bacteriocin production represents a probiotic trait for
intestinal strains to promote dominance, fight infection, and even signal the immune system. …

Efficacy of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis and advanced lung disease

KM O'Shea, OM O'Carroll, C Carroll… - European …, 2021 - Eur Respiratory Soc
Cystic fibrosis (CF) is an autosomal recessive disorder which results from mutations in the
cystic fibrosis transmembrane regulator (CFTR) gene encoding the CFTR protein. Defects in …

Comparison of Volumetric and Bead‐Based Counting of CD34 Cells by Single‐Platform Flow Cytometry

…, A Ruf, A Engel, YZ Zhang, O O'Shea… - Cytometry Part B …, 2019 - Wiley Online Library
Background Over 2,000 people a year in the United Kingdom need a bone marrow or blood
stem cell transplant. It is important to accurately quantify the hematopoietic stem cells to …

Bactofencin A, a new type of cationic bacteriocin with unusual immunity

EF O'Shea, PM O'Connor, O O'Sullivan, PD Cotter… - MBio, 2013 - Am Soc Microbiol
Bacteriocin production is an important probiotic trait of intestinal bacteria. In this study, we
identify a new type of bacteriocin, bactofencin A, produced by a porcine intestinal isolate …