There is convincing epidemiological and clinical evidence that, independent of aging, lifestyle
and, notably, nutrition are associated with development or progression of major human …

OBJECTIVE: It has been proposed that physiologic levels of estrogens stimulate immune
responses whereas androgens suppress inflammatory reactions. Thus, prevalence of synovial …

Breast cancer incidence and mortality rates are markedly lower in the south than in the north
of Europe. This has been ascribed to differences in lifestyle and, notably, dietary habits …

The relationship between sex steroids and cancer has been studied for more than a century.
Using an original intact cell analysis, we investigated sex steroid metabolism in a panel of …

The product of neurofibromatosis type 2 (NF2) gene, also known as Merlin/neurofibromin 2,
homeostatically regulates liver stem cells by controlling abundance and signaling of …

Purpose: The main goal of our study was to assess estrogen contents of breast tumor tissues,
having different estrogen receptor status, in relation to long-term follow-up of patients. …

Catecholestrogens (CCEs), namely 2- or 4-hydroxyestradiol and hydroxyestrone, are highly
polar, reactive, and extremely labile estrogen metabolites in many experimental conditions. …

The 17β-hydroxysteroid dehydrogenase (17βHSD) enzyme system governs important redox
reactions at the C17 position of steroid hormones. Different 17βHSD types (no. 1–4) have …

Our previous studies are reviewed and at the same time preliminary experimental observation
to the topic of endocrine end‐points in autoimmune disease is introduced. To this end, we …

In recent years there has been a continuingly increasing interest in novel research subjects,
as yet poorly explored, either because they relate to aspects previously thought to be …