In this paper we present a computation of the mean first-passage times both for a random
walk in a discrete bounded lattice, between a starting site and a target site, and for a Brownian …

This review examines intermittent target search strategies, which combine phases of slow
motion, allowing the searcher to detect the target, and phases of fast motion during which …

Albers-Schönberg disease, or autosomal dominant osteopetrosis, type II (ADO II), is the
most common form of osteopetrosis, a group of conditions characterized by an increased …

How long must one undertake a random search to visit all sites of a given domain? This time,
known as the cover time 1 , is a key observable to quantify the efficiency of exhaustive …

We present a general theory which allows one to accurately evaluate the mean first-passage
time (FPT) for regular random walks in bounded domains, and its extensions to related first-…

An increasing number of experimental studies employ single particle tracking to probe the
physical environment in complex systems. We here propose and discuss what we believe are …

Bone is a dynamic tissue that is subject to the balanced processes of bone formation and
bone resorption. Imbalance can give rise to skeletal pathologies with increased bone density. …

Cell movement has essential functions in development, immunity, and cancer. Various cell
migration patterns have been reported, but no general rule has emerged so far. Here, we …

Background Myostatin inhibits skeletal muscle growth. The humanised monoclonal antibody
LY2495655 (LY) binds and neutralises myostatin. We aimed to test whether LY increases …

10.7554/eLife.02230.001 Gene regulation relies on transcription factors (TFs) exploring the
nucleus searching their targets. So far, most studies have focused on how fast TFs diffuse, …