In the weeks after birth, the gut acquires a nascent microbiome, and starts its transition to
bacterial population equilibrium. This early-in-life microbial population quite likely influences …

Objective The technology for the growth of human intestinal epithelial cells is rapidly
progressing. An exciting possibility is that this system could serve as a platform for individualised …

Background Gut bacteria might predispose to or protect from necrotising enterocolitis, a severe
illness linked to prematurity. In this observational prospective study we aimed to assess …

As it descended from Escherichia coli O55:H7, Shiga toxin (Stx)-producing E. coli (STEC)
O157:H7 is believed to have acquired, in sequence, a bacteriophage encoding Stx2 and …

Bacteria that cause late-onset neonatal sepsis often reside in the infant gut before they invade
the bloodstream. They are rarely found in infants without sepsis. Screening, augmented …

Background . The etiology of childhood diarrhea is frequently unknown. Methods . We
sought Aeromonas, Campylobacter, Escherichia coli O157:H7, Pleisiomonas shigelloides, …

The role of the Escherichia coli iron-regulated gene homologue adhesin (Iha) in the pathogenesis
of urinary tract infections (UTIs) is unknown. We performed a series of complementary …

Background & Aims Inflammation, injury, and infection up-regulate expression of the tryptophan
metabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1) in the intestinal epithelium. …

Single nucleotide polymorphisms (SNPs) in stable genome regions provide durable
measurements of species evolution. We systematically identified each SNP in concatenations of all …

Escherichia coli O157:H7, a zoonotic human pathogen for which domestic cattle are a
reservoir host, produces a Shiga toxin(s) (Stx) encoded by bacteriophages. Chromosomal …