PTEN is an important tumor suppressor gene. Hereditary mutation of PTEN causes tumor-susceptibility
diseases such as Cowden disease. We used the Cre-loxP system to generate an …

Fas is a cell-surface receptor molecule that relays apoptotic (cell death) signals into cells.
When Fas is activated by binding of its ligand, the proteolytic protein caspase-8 is recruited to a …

The human serine/threonine kinase, mammalian STE20-like kinase (MST), is considerably
homologous to the budding yeast kinases, SPS1 and STE20, throughout their kinase domains…

Chemokines play an essential role in the progression of rheumatoid arthritis (RA). In the
present study we examined the expression and regulatory mechanisms of IFN-γ inducible …

PTEN is a tumor suppressor gene mutated in many human cancers. We generated a
bronchioalveolar epithelium–specific null mutation of Pten in mice [SP-C-rtTA/(tetO) 7 -Cre/Pten flox/…

Objective: We aimed to analyze the clinical and histopathologic features of cancer-associated
myositis (CAM) in relation to anti–transcriptional intermediary factor 1 γ antibody (anti-TIF1-…

PTEN is a tumor suppressor gene mutated in many human cancers. We used the Cre-loxP
system to generate an urothelium-specific null mutation of Pten in mice [FabpCrePten flox/flox …

The aim of this book is to introduce scientific ballooning to the many people who are interested
in the use of balloons for scientific applications. The book offers a basic understanding of …

Objective To determine levels of the soluble form of the chemokine fractalkine (sFkn) and its
receptor, CX 3 CR1, in patients with systemic lupus erythematosus (SLE) with …

Objective To determine levels of soluble fractalkine (sFkn) in rheumatoid arthritis (RA) patients
with and without rheumatoid vasculitis (RV), and to assess the relationship of sFkn levels …