American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone …

…, G Francis, NS Goldstein… - … of pathology & …, 2010 - meridian.allenpress.com
Purpose.—To develop a guideline to improve the accuracy of immunohistochemical (IHC)
estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the …

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model.

NI Goldstein, M Prewett, K Zuklys, P Rockwell… - Clinical cancer research …, 1995 - AACR
The epidermal growth factor receptor (EGFR) is a protein tyrosine kinase expressed on
many types of tumor cells, including breast, ovarian, bladder, head and neck, and prostatic …

[HTML][HTML] Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis

…, B Zhou, S Li, LT Dooley, NH Goldstein… - … England Journal of …, 2010 - Mass Medical Soc
Background Biologic agents offer a range of new therapeutic options for patients with
psoriasis; however, the relative benefit–risk profiles of such therapies are not well known. We …

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by …

…, J Rak, MC Hung, P Rockwell, N Goldstein… - The American journal …, 1997 - ncbi.nlm.nih.gov
The overexpression in tumor cells of (proto)-oncogenic receptor tyrosine kinases such as
epidermal growth factor receptor (EGFR) or ErbB2/neu (also known as HER-2) is generally …

Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis

…, W Xu, D Baker, N Goldstein… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To evaluate the effect of infliximab on progression of structural damage over 2 years
in patients with ankylosing spondylitis (AS). Methods In the Ankylosing Spondylitis Study …

Halting angiogenesis suppresses carcinoma cell invasion

M Skobe, P Rockwell, N Goldstein, S Vosseler… - Nature medicine, 1997 - nature.com
The importance of angiogenesis in malignant tumor growth has been interpreted mainly in
terms of oxygen and nutrient supply. Here we demonstrate its fundamental role for tumor …

The melanoma differentiation associated gene mda-7 suppresses cancer cell growth.

H Jiang, ZZ Su, JJ Lin, NI Goldstein… - Proceedings of the …, 1996 - National Acad Sciences
Cancer is a disease characterized by defects in growth control, and tumor cells often display
abnormal patterns of cellular differentiation. The combination of recombinant human …

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

…, S Kitada, JC Reed, NI Goldstein… - Proceedings of the …, 1998 - National Acad Sciences
A differentiation induction subtraction hybridization strategy is being used to identify and clone
genes involved in growth control and terminal differentiation in human cancer cells. This …

The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma.

…, J Mendelsohn, HI Scher, NI Goldstein - … with emphasis on …, 1996 - europepmc.org
For prostate cancer, a correlation exists between overexpression of the epidermal growth
factor receptor (EGFR) and poor clinical prognosis. In addition, late-stage metastatic disease is …

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth …

…, MX Mei, KA Christiansen, F Sivo, NI Goldstein… - Oncogene, 2001 - nature.com
Abnormalities in cellular differentiation are frequent occurrences in human cancers. Treatment
of human melanoma cells with recombinant fibroblast interferon (IFN-β) and the protein …