Chronic kidney disease (CKD) is recognized as an irreversible reduction of functional
nephrons and leads to an increased risk of various pathological conditions, including …

Chronic kidney disease (CKD) is characterized by kidney damage with proteinuria,
hematuria, and progressive loss of kidney function. The final stage of CKD is known as end-stage …

Bladder cancer (BC) is a representative of urological cancer with a high recurrence and
metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint inhibitors …

Urinary dysfunction is a common pathological condition that can significantly decrease the
quality of life. Bladder outlet obstruction (BOO) is a major cause of urinary dysfunction, and …

Introduction Human antigen R (HuR) regulates the stability of mRNA and is associated with
cell proliferation, angiogenesis, and lymphangiogenesis. However, the clinical significance …

Benign prostatic hyperplasia (BPH) is arguably the most common benign disease among
men. This disease is often associated with lower urinary tract symptoms (LUTS) in men and …

Molecular targeted therapies are commonly used in patients with metastatic renal cell
carcinoma (RCC). However, the efficacy and safety of these therapeutic interventions require …

Aims: Twist has been reported to play crucial roles for malignant aggressiveness; however,
detailed pathological significance of Twist in renal cell carcinoma (RCC) is not fully …

We followed 207 patients with rheumatoid arthritis who were registered at our hospital over a
10-year period from between 1989 and 1990. The number of patients who were still treated …

Prostaglandin E2 plays an important role in carcinogenesis and malignant potential of prostate
cancer (PC) cells by binding to its specific receptors, E-type prostanoid (EP) receptors. …