The COVID-19 pandemic is challenging our cardiovascular care of patients with heart
diseases. In the setting of pericardial diseases, there are two possible different scenarios to …

Type I IFN (IFN-I) was firstly described in 1957 as a soluble factor responsible for viral
resistance in vitro. Today, it is well known that the IFN-I family comprises a wide number of …

Objective. To evaluate the development of hepatitis B virus (HBV) infection in patients receiving
tumor necrosis factor-α-blocking agents (TNFBA), and to evaluate whether lamivudine (…

Objectives The outbreak of COVID-19 posed the issue of urgently identifying treatment
strategies. Colchicine was considered for this purpose based on well-recognised anti-…

Objective. Abatacept (ABA) is a chimeric molecule, able to block the CD28-mediated costimulatory
pathway. To evaluate the hypothesis that, through this mechanism of action, ABA may …

Few data are available to assess the efficacy of rehabilitative interventions in systemic sclerosis
(SSc). We refer here the results of an individualized rehabilitation program in 16 patients …

Objective. To verify the hypothesis that blockade of CD28 costimulation by treatment with
abatacept in patients with rheumatoid arthritis (RA) might induce a reduction in the number of …

Objective. To evaluate the number of circulating CD28-negative (CD28–) T cells as a
predictor of clinical response to abatacept in patients with rheumatoid arthritis (RA). Methods. …

Objective To evaluate whether the addition of colchicine to standard of care (SOC) results in
better outcomes in hospitalized patients with COVID-19. Design This interventional, …

… Laura Andreoli and Mirko Scarsi contributed equally to this … Franceschini, Laura Andreoli,
Mirko Scarsi, Why not to use … Laura Andreoli and Mirko Scarsi contributed equally to this …