Key contribution of CPEB4-mediated translational control to cancer progression

…, M Iglesias, F Alameda, M Moreno… - Nature medicine, 2012 - nature.com
Malignant transformation, invasion and angiogenesis rely on the coordinated reprogramming
of gene expression in the cells from which the tumor originated. Although deregulated …

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk

…, J Vinaixa, T Dalotto-Moreno… - Proceedings of the …, 2018 - National Acad Sciences
Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with
extremely low survival rates due to late diagnosis and resistance to standard therapies. A …

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

N Martínez-Bosch, MG Fernández-Barrena, M Moreno… - Cancer research, 2014 - AACR
Despite some advances, pancreatic ductal adenocarcinoma (PDAC) remains generally
refractory to current treatments. Desmoplastic stroma, a consistent hallmark of PDAC, has …

[HTML][HTML] Influence of HLA-B27 on the Ankylosing Spondylitis phenotype: results from the REGISPONSER database

M Arévalo, J Gratacós Masmitjà, M Moreno… - Arthritis research & …, 2018 - Springer
Objective To assess HLA-B27 influence on the clinical phenotype of Ankylosing Spondylitis (AS)
patients. Method An observational, cross-sectional and descriptive study of AS patients …

[HTML][HTML] Efficacy of anakinra in refractory adult-onset Still's disease: multicenter study of 41 patients and literature review

…, J del Blanco-Barnusell, JR De Dios, M Moreno… - Medicine, 2015 - journals.lww.com
Efficacy of Anakinra in Refractory Adult-Onset Still's Disea... : Medicine Efficacy of Anakinra in
Refractory Adult-Onset Still's Disease: Multicenter Study of 41 Patients and Literature Review …

Sex-associated and gender-associated differences in the diagnosis and management of axial spondyloarthritis: addressing the unmet needs of female patients

…, E Gremese, U Kiltz, E Lubrano, M Moreno… - RMD open, 2021 - rmdopen.bmj.com
Emerging evidence suggests that axial spondyloarthritis (axSpA) should not be seen as a
predominantly male disease, as the non-radiographic form occurs with roughly equal …

[HTML][HTML] Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

…, J Earl, A Carrato, N Manero-Rupérez, M Moreno… - …, 2022 - thelancet.com
Background Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC).
The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble …

[PDF][PDF] Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling

…, N Pozo, A Laguna, S Aranda, E Porlan, M Moreno… - Cell stem cell, 2010 - cell.com
Stem cell division can result in two sibling cells exhibiting differential mitogenic and self-renewing
potential. Here, we present evidence that the dual-specificity kinase Dyrk1A is part of a …

[HTML][HTML] Comprehensive description of clinical characteristics of a large systemic lupus erythematosus cohort from the Spanish Rheumatology Society Lupus Registry …

…, G Bonilla, V Torrente, I Castellví, J Alegre, M Moreno… - Medicine, 2015 - journals.lww.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ involvement and pronounced racial and ethnic heterogeneity. The aims of the present …

[HTML][HTML] Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission

…, A Llobell, E Graell, M García-Manrique, M Moreno… - Scientific reports, 2022 - nature.com
COVID-19 pathophysiology is currently not fully understood, reliable prognostic factors
remain elusive, and few specific therapeutic strategies have been proposed. In this scenario, …