User profiles for Michele M. Luchetti

Michele Maria Luchetti

Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ancona …
Verified email at univpm.it
Cited by 4301

Abnormal liver function tests predict transfer to intensive care unit and death in COVID‐19

…, A Mantovani, A Martini, MM Luchetti… - Liver …, 2020 - Wiley Online Library
Background The pandemic of coronavirus disease 2019 (COVID‐19) has emerged as a
relevant threat for humans worldwide. Abnormality in liver function tests (LFTs) has been …

Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland

…, C Pisoschi, MM Luchetti, M Marelli… - Proceedings of the …, 2004 - National Acad Sciences
Mammalian breast adipose tissue is replaced by a milk-secreting gland during pregnancy;
the reverse process takes place upon interruption of lactation. Morphological and …

[HTML][HTML] Monocytes of patients with systemic sclerosis (scleroderma) spontaneously release in vitro increased amounts of superoxide anion

…, L Jannino, M Candela, A Salvi, MM Luchetti… - Journal of Investigative …, 1999 - Elsevier
It has been suggested that toxic oxygen free radicals can be involved in the pathogenesis of
systemic sclerosis (scleroderma) (SSc). Because the cells that contribute to the generation …

Musculoskeletal and rheumatic diseases induced by immune checkpoint inhibitors: a review of the literature

D Benfaremo, L Manfredi, MM Luchetti… - Current drug …, 2018 - ingentaconnect.com
Background: Immune checkpoint inhibitors are a new promising class of antitumor drugs that
have been associated with a number of immune-related Adverse Events (AEs), including …

Induction of Scleroderma Fibrosis in Skin‐Humanized Mice by Administration of Anti− Platelet‐Derived Growth Factor Receptor Agonistic Autoantibodies

MM Luchetti, G Moroncini… - Arthritis & …, 2016 - Wiley Online Library
Objective To describe a skin–SCID mouse chimeric model of systemic sclerosis (SSc;
scleroderma) fibrosis based on engraftment of ex vivo–bioengineered skin using skin cells derived …

[HTML][HTML] Successful treatment of a Caucasian case of multifocal Castleman's disease with TAFRO syndrome with a pathophysiology targeted therapy-a case report

…, L Manfredi, G Goteri, MM Luchetti… - … hematology & oncology, 2015 - Springer
… Therefore, R-CVP (rituximab 375 mg/m 3 , cyclophosphamide 750 mg/m 3 , vincristine
1.4 mg/m 3 and prednisone 40 mg/m 3 ) chemotherapy was started (CVP monthly; rituximab …

Management of concomitant inflammatory bowel disease or uveitis in patients with psoriatic arthritis: an updated review informing the 2021 GRAPPA treatment …

…, J Hutton, D O'Sullivan, MM Luchetti, M Stoll… - The Journal of …, 2023 - jrheum.org
Objective Several advanced therapies have been licensed across the related conditions of
psoriatic arthritis (PsA), Crohn disease (CD), ulcerative colitis (UC), and noninfectious uveitis. …

Biologics in inflammatory and immunomediated arthritis

MM Luchetti, D Benfaremo… - Current pharmaceutical …, 2017 - ingentaconnect.com
Background: Biologic drugs, introduced in clinical practice almost twenty years ago, represent
nowadays a prominent treatment option in patients with chronic inflammatory arthritis, …

Dissociation between p93B-myb and p75c-myb expression during the proliferation and differentiation of human myeloid cell lines

M Arsura, MM Luchetti, E Erba, J Golay, A Rambaldi… - 1994 - ashpublications.org
Direct and indirect evidence strongly indicates that the proto-oncogene c-myb plays an
important role in the regulation of both the proliferation and differentiation of hematopoietic cells. …

[HTML][HTML] Characterization of the c-Myb-responsive region and regulation of the human type I collagen α2 chain gene by c-Myb

MM Luchetti, P Paroncini, P Majlingova… - Journal of Biological …, 2003 - ASBMB
We have characterized the role of c-Myb and B-Myb in the regulation of human type I collagen
α2 chain gene expression in fibroblastic cells. We have identified four Myb-binding sites (…