Adalimumab, a fully human anti–tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the …

ME Weinblatt, EC Keystone, DE Furst… - Arthritis & …, 2003 - Wiley Online Library
Weinblatt has also received honoraria as a member of the scientific advisory board and as a
Weinblatt has also received honoraria as a member of the scientific advisory board and as a …

Principal components analysis corrects for stratification in genome-wide association studies

AL Price, NJ Patterson, RM Plenge, ME Weinblatt… - Nature …, 2006 - nature.com
Population stratification—allele frequency differences between cases and controls due to
systematic ancestry differences—can cause spurious associations in disease studies. We …

2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis

…, S Venkatachalam, ME Weinblatt… - Arthritis & …, 2021 - Wiley Online Library
Objective To develop updated guidelines for the pharmacologic management of rheumatoid
arthritis. Methods We developed clinically relevant population, intervention, comparator, …

Etanercept therapy in rheumatoid arthritis: a randomized, controlled trial

…, MLM Lange, ND McDonnell, ME Weinblatt - Annals of internal …, 1999 - acpjournals.org
Background: In a phase II study, etanercept (recombinant human tumor necrosis factor
receptor [p75]:Fc fusion protein) safely produced rapid, dose-dependent improvement in …

[HTML][HTML] A trial of etanercept, a recombinant tumor necrosis factor receptor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

ME Weinblatt, JM Kremer, AD Bankhurst… - … England Journal of …, 1999 - Mass Medical Soc
Background Patients treated with methotrexate for rheumatoid arthritis often improve but
continue to have active disease. This study was undertaken to determine whether the addition …

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

…, CE van der Schoot, PLCM van Riel, ME Weinblatt… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Platelets amplify inflammation in arthritis via collagen-dependent microparticle production

…, ME Weinblatt, EM Massarotti, E Remold-O'Donnell… - Science, 2010 - science.org
In addition to their pivotal role in thrombosis and wound repair, platelets participate in
inflammatory responses. We investigated the role of platelets in the autoimmune disease …

Efficacy of low-dose methotrexate in rheumatoid arthritis

ME Weinblatt, JS Coblyn, DA Fox… - … England Journal of …, 1985 - Mass Medical Soc
Twenty-eight patients with refractory rheumatoid arthritis completed a randomized 24-week
double-blind crossover trial comparing oral methotrexate (2.5 to 5 mg every 12 hours for …

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

…, K Wei, F Mizoguchi, NC Teslovich, ME Weinblatt… - Nature, 2017 - nature.com
CD4 + T cells are central mediators of autoimmune pathology; however, defining their key
effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4 + T …

Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin‐1 receptor antagonist, in combination with methotrexate: results of a twenty‐four …

…, E Hurd, J Cush, M Schiff, ME Weinblatt… - Arthritis & …, 2002 - Wiley Online Library
Objective To evaluate the efficacy and safety of anakinra in combination with methotrexate (MTX)
in patients with active rheumatoid arthritis (RA). Methods Patients with moderate‐to‐…