Background Previous studies have shown that alendronate can increase bone mineral
density (BMD) and prevent radiographically defined (morphometric) vertebral fractures. The …

The assessment of vertebral fracture by conventional radiography has been refined and
improved using either semiquantitative or quantitative criteria. The inter‐ and intraobserver …

Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry. …

Background Many risk factors for hip fractures have been suggested but have not been
evaluated in a comprehensive prospective study. Methods We assessed potential risk factors, …

Falls are a major threat to the health of older persons. We evaluated potential risk factors for
falls in 325 community-dwelling persons aged 60 years or older who had fallen during the …

Osteoarthritis (OA) is the most common joint disorder in the world. In Western populations it
is one of the most frequent causes of pain, loss of function and disability in adults. …

We examined the effect of alendronate treatment for 3–4 yr on risk of new fracture among
3658 women with osteoporosis enrolled in the Fracture Intervention Trial. This cohort included …

Background Osteoporotic fractures, including clinically detected vertebral fractures, are
associated with increased mortality. However, only one third of vertebral fractures are diagnosed. …

We conducted a prospective study of the consequences of falls in 325 elderly community-dwelling
persons, all of whom had fallen in the previous year. We contacted subjects every …

To determine whether measurement of bone density predicts hip fracture in women, we
prospectively studied 9703 nonblack women aged 65 years and older who had measurements …