User profiles for Merry-Lynn McDonald
Merry-Lynn Noelle McDonaldAssociate Professor, University of Alabama at Birmingham Verified email at uab.edu Cited by 4432 |
The clinical and genetic features of COPD-asthma overlap syndrome
M Hardin, M Cho, ML McDonald, T Beaty… - European …, 2014 - Eur Respiratory Soc
Individuals with chronic obstructive pulmonary disease (COPD) and asthma are an important
but poorly characterised group. The genetic determinants of COPD and asthma overlap …
but poorly characterised group. The genetic determinants of COPD and asthma overlap …
Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease
Background Eosinophilic airway inflammation in patients with chronic obstructive pulmonary
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …
[HTML][HTML] A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
Background Pulmonary function decline is a major contributor to morbidity and mortality
among smokers. Post bronchodilator FEV 1 and FEV 1 /FVC ratio are considered the standard …
among smokers. Post bronchodilator FEV 1 and FEV 1 /FVC ratio are considered the standard …
[HTML][HTML] The Chicken Frizzle Feather Is Due to an α-Keratin (KRT75) Mutation That Causes a Defective Rachis
CS Ng, P Wu, J Foley, A Foley, ML McDonald… - PLoS …, 2012 - journals.plos.org
Feathers have complex forms and are an excellent model to study the development and
evolution of morphologies. Existing chicken feather mutants are especially useful for identifying …
evolution of morphologies. Existing chicken feather mutants are especially useful for identifying …
Potential role of modifier genes influencing transforming growth factor-β1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary …
A Bourdeau, ME Faughnan, ML McDonald… - The American journal of …, 2001 - Elsevier
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder because
of mutations in the genes coding for endoglin (HHT1) or ALK-1 (HHT2). The disease is …
of mutations in the genes coding for endoglin (HHT1) or ALK-1 (HHT2). The disease is …
Machine learning characterization of COPD subtypes: insights from the COPDGene study
COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there
is not yet consensus on how many COPD subtypes there are and how they should be …
is not yet consensus on how many COPD subtypes there are and how they should be …
Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers
AA Diaz, L Zhou, TP Young, ML McDonald… - Academic radiology, 2014 - Elsevier
Rationale and Objectives Computed tomography (CT) of the chest can be used to assess
pectoralis muscle area (PMA) and subcutaneous adipose tissue (SAT) area. Adipose tissue …
pectoralis muscle area (PMA) and subcutaneous adipose tissue (SAT) area. Adipose tissue …
[HTML][HTML] Pectoralis muscle area and mortality in smokers without airflow obstruction
…, R Harmouche, TP Young, ML McDonald… - Respiratory …, 2018 - Springer
Background Low muscle mass is associated with increased mortality in the general population
but its prognostic value in at-risk smokers, those without expiratory airflow obstruction, is …
but its prognostic value in at-risk smokers, those without expiratory airflow obstruction, is …
The St. George's Respiratory Questionnaire definition of chronic bronchitis may be a better predictor of COPD exacerbations compared with the classic definition
Background Chronic bronchitis (CB) increases risk of COPD exacerbations. We have shown
that the St. George’s Respiratory Questionnaire (SGRQ) CB definition identifies patients …
that the St. George’s Respiratory Questionnaire (SGRQ) CB definition identifies patients …
Lobar emphysema distribution is associated with 5-year radiological disease progression
…, N Hansel, C Hersh, P Castaldi, ML McDonald… - Chest, 2018 - Elsevier
Background Emphysema has considerable variability in its regional distribution. Craniocaudal
emphysema distribution is an important predictor of the response to lung volume reduction…
emphysema distribution is an important predictor of the response to lung volume reduction…