During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been
deployed globally. We investigated whether antibodies stimulated by mRNA vaccination (…

Immune checkpoint inhibitors (CPIs), monoclonal antibodies that target inhibitory receptors
expressed on T cells, represent an emerging class of immunotherapy used in treating solid …

Background Previous studies have independently validated the prognostic relevance of
residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from several …

Here we report the discovery of oncogenic mutations in the Hedgehog and mitogen-activated
protein kinase (MAPK) pathways in over 80% of ameloblastomas, locally destructive …

Rationale & Objective Kidney biopsy data inform us about pathologic processes associated
with infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We …

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with characteristic
tumors involving multiple organ systems. Whereas renal angiomyolipoma (AML) is common in …

The purpose is to compare quantitative dynamic contrast-enhanced (DCE) magnetic
resonance imaging (MRI) metrics with imaging tumor size for early prediction of breast cancer …

Importance Residual cancer burden (RCB) distributions may improve the interpretation of
efficacy in neoadjuvant breast cancer trials. Objective To compare RCB distributions between …

Mutationally activated protein kinases are appealing therapeutic targets in breast carcinoma.
Mutations in phosphatidylinositol-3-kinase (PI3KCA) have been described in 8–40% of …

Papillary lesions of the breast have an uncertain relationship to the histogenesis of breast
carcinoma, and are thus diagnostically and managerially challenging. Molecular genetic …