OBJECTIVE: This study was undertaken to determine the risk of rare complications during
pregnancy for women with systemic lupus erythematosus. STUDY DESIGN: By using the …

Objective Hydroxychloroquine (HCQ) is often needed to manage disease activity in systemic
lupus erythematosus (SLE) during pregnancy. The purpose of this study was to examine …

Objective To develop an evidence‐based guideline on contraception, assisted reproductive
technologies ( ART ), fertility preservation with gonadotoxic therapy, use of menopausal …

Objective Systemic lupus erythematosus is associated with multiple adverse pregnancy
outcomes. We examined the impact of disease activity on spontaneous abortions, perinatal …

Pregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both
lupus activity and pregnancy mishaps. The majority of recent studies found an increase in …

Purpose: Treatment with cyclophosphamide (CYC) confers up to a 40% risk of ovarian failure
in women of reproductive age. The use of GnRH agonists (GnRHa) to preserve ovarian …

Throughout the last decade, increasing awareness has been raised on issues related to
reproduction in rheumatic diseases including basic research to clarify the important role of …

Objective Women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
have fewer children on average than other women. We sought to determine the roles of …

Background Women with chronic inflammatory diseases face uncertainty regarding the
safety of biologics during breast feeding. CRADLE was the first industry-sponsored study to …

Objective Epratuzumab, a monoclonal antibody that targets CD22, modulates B cell signaling
without substantial reductions in the number of B cells. The aim of this study was to report …