Interleukin-12 (IL-12), a heterodimeric cytokine produced by activated monocytes and dendritic
cells, plays a crucial role in regulating interferon (IFN)-γ production and in the generation …

for digital applications (smartphones, etc.). These versions are abridged and thus, for more
detailed information, the user should always access to the full text version of the guidelines, …

Background Few studies have examined the causes of syncope/collapse recurrences in
patients with a previously implanted pacemaker for bradyarrhythmic syncope. Objective The …

AF and the Risk of Thromboembolic Events. Introduction: Asymptomatic atrial fibrillation (AF)
can expose patients to the risk of stroke. The primary objective of this study was to assess …

Gene silencing is instrumental to interrogate gene function and holds promise for therapeutic
applications. Here, we repurpose the endogenous retroviruses' silencing machinery of …

Objective The persistence of a left superior vena cava(LSVC) has been observed in 0.3% of
the general population asestablished by autopsy. In the adult population, it is an …

A thrombin-like serine protease, jararassin-I, was isolated from the venom of Bothrops jararaca.
The protein was obtained in high yield and purity by a single chromatographic step using …

Background Infections after placement of cardiac implantable electronic devices (CIEDs)
are associated with substantial morbidity and mortality. There is limited evidence on …

Type I IFNs (IFN-α/β), in addition to IL-12, have been shown to play an important role in the
differentiation of human, but not mouse, Th cells. We show here that IFN-α/β act directly on …

Background and Purpose— In patients with atrial fibrillation (AF), stroke risk stratification
schema do not consider AF parameters. The aim of the study is to assess the impact of …