The phenotype and genotype of mevalonate kinase deficiency: a series of 114 cases from the Eurofever registry
…, A Simon, PA Brogan, M Doglio… - Arthritis & …, 2016 - Wiley Online Library
Objective Mevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by
recurrent inflammatory episodes. This study was undertaken to describe the genotype, …
recurrent inflammatory episodes. This study was undertaken to describe the genotype, …
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function
T cell receptor (TCR)–based therapy has the potential to induce durable clinical responses
in patients with cancer by targeting intracellular tumor antigens with high sensitivity and by …
in patients with cancer by targeting intracellular tumor antigens with high sensitivity and by …
[HTML][HTML] A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
Background Hereditary recurrent fevers (HRF) are a group of rare monogenic diseases
leading to recurrent inflammatory flares. A large number of variants has been described for the …
leading to recurrent inflammatory flares. A large number of variants has been described for the …
Performance of different diagnostic criteria for familial Mediterranean fever in children with periodic fevers: results from a multicenter international registry
…, T Turker, I Koné-Paut, P Woo, M Doglio… - The Journal of …, 2016 - jrheum.org
Objective. Our aims were to validate the pediatric diagnostic criteria in a large international
registry and to compare them with the performance of previous criteria for the diagnosis of …
registry and to compare them with the performance of previous criteria for the diagnosis of …
CD4+ memory stem T cells recognizing citrullinated epitopes are expanded in patients with rheumatoid arthritis and sensitive to tumor necrosis factor blockade
…, ZI Magnani, M Baldini, M Doglio… - Arthritis & …, 2020 - Wiley Online Library
Objective Memory stem T (Tscm) cells are long‐lived, self‐renewing T cells that play a
relevant role in immunologic memory. This study was undertaken to investigate whether Tscm …
relevant role in immunologic memory. This study was undertaken to investigate whether Tscm …
[HTML][HTML] Lymphodepletion–an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle
…, L Warmuth, P Barba, M Doglio… - Frontiers in …, 2023 - frontiersin.org
Lymphodepletion (LD) or conditioning is an essential step in the application of currently
used autologous and allogeneic chimeric antigen receptor T-cell (CAR-T) therapies as it …
used autologous and allogeneic chimeric antigen receptor T-cell (CAR-T) therapies as it …
[HTML][HTML] New insights in systemic lupus erythematosus: from regulatory T cells to CAR-T-cell strategies
M Doglio, T Alexander, N Del Papa… - Journal of Allergy and …, 2022 - Elsevier
Systemic lupus erythematous is a heterogeneous autoimmune disease with potentially
multiorgan damage. Its complex etiopathogenesis involves genetic, environmental, and …
multiorgan damage. Its complex etiopathogenesis involves genetic, environmental, and …
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir
G Orofino, E Xue, M Doglio, M Noviello… - Bone Marrow …, 2023 - nature.com
Cytomegalovirus (CMV) reactivations are strong stimulators of immune-reconstitution (IR) in
hematopoietic stem cell transplantation (HSCT) recipients. Herein, we analyzed 317 CMV-…
hematopoietic stem cell transplantation (HSCT) recipients. Herein, we analyzed 317 CMV-…
[HTML][HTML] Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated bacillus Calmette …
…, F Ferrua, M Migliavacca, V Calbi, M Doglio… - …, 2021 - ncbi.nlm.nih.gov
… Francesca Tucci, 1, 2, * Vera Gallo, 1, 2, * Federica Barzaghi, 1, 2 Francesca Ferrua, 1, 2
Maddalena Migliavacca, 1, 2 Valeria Calbi, 1, 2 Matteo Doglio, 1 Elena Sophia Fratini, 1, 3 …
Maddalena Migliavacca, 1, 2 Valeria Calbi, 1, 2 Matteo Doglio, 1 Elena Sophia Fratini, 1, 3 …
[HTML][HTML] Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on cytomegalovirus reactivation risk after …
…, P De Simone, MT Lupo-Stanghellini, M Doglio… - …, 2023 - ncbi.nlm.nih.gov
After allogeneic hematopoietic stem cell transplantation (HSCT), the emergence of circulating
cytomegalovirus (CMV)-specific T cells correlates with protection from CMV reactivation, …
cytomegalovirus (CMV)-specific T cells correlates with protection from CMV reactivation, …