Objective Gout, caused by hyperuricaemia, is a multifactorial disease. Although genome-wide
association studies (GWASs) of gout have been reported, they included self-reported gout …

Gout is a common disease which results from hyperuricemia. We have reported that the
dysfunction of urate exporter ABCG2 is the major cause of renal overload (ROL) hyperuricemia, …

Gout is a common disease which mostly occurs after middle age, but more people nowadays
develop it before the age of thirty. We investigated whether common dysfunction of ABCG2, …

Objective A genome-wide association study (GWAS) of gout and its subtypes was performed
to identify novel gout loci, including those that are subtype-specific. Methods Putative …

Noise-induced hearing loss (NIHL) is one of the most common sensorineural hearing deficits.
Recent studies have demonstrated that the pathogenesis of NIHL is closely related to …

Objective The first ever genome-wide association study (GWAS) of clinically defined gout
cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel gout …

Objective Serum uric acid (SUA) levels in humans are mainly regulated by urate transporters.
Recent genome‐wide association studies suggested that common variants of the human …

Gout/hyperuricemia is a common multifactorial disease having typical environmental risks.
Recently, common dysfunctional variants of ABCG2, a urate exporter gene also known as …

Gout is a common disease caused by hyperuricemia, which shows elevated serum uric acid
(SUA) levels. From a viewpoint of urate handling in humans, gout patients can be divided …

Objective Previous studies have suggested an association between gout susceptibility and
common dysfunctional variants in ATP-binding cassette transporter subfamily G member 2/…