Electron in a cube: Synthesis and characterization of perfluorocubane as an electron acceptor

M Sugiyama, M Akiyama, Y Yonezawa, K Komaguchi… - Science, 2022 - science.org
Fluorinated analogs of polyhedral hydrocarbons have been predicted to localize an electron
within their cages upon reduction. Here, we report the synthesis and characterization of …

Anti-inflammatory effect of all-trans-retinoic acid in inflammatory arthritis

Y Nozaki, T Yamagata, M Sugiyama, S Ikoma… - Clinical …, 2006 - Elsevier
OBJECTIVE:: To determine whether all-trans-retinoic acid (ATRA) improves the destruction
of joints and the effect of cytokines on DBA/1J mice with collagen-induced arthritis (CIA). …

Retinoic acid reduces autoimmune renal injury and increases survival in NZB/W F1 mice

K Kinoshita, BS Yoo, Y Nozaki, M Sugiyama… - The Journal of …, 2003 - journals.aai.org
Retinoic acids, a group of natural and synthetic vitamin A derivatives, have potent antiproliferative
and anti-inflammatory properties. Recently, retinoic acids were reported to inhibit Th1 …

[HTML][HTML] Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis after COVID-19 vaccination

S Okuda, Y Hirooka, M Sugiyama - Vaccines, 2021 - mdpi.com
We report the case of a patient who developed antineutrophil cytoplasmic antibody (ANCA)-associated
vasculitis (AAV) after receiving the coronavirus disease 2019 (COVID-19) …

Blockade of IL-18 receptor signaling delays the onset of autoimmune disease in MRL-Faslpr mice

…, T Yamagata, Y Nozaki, M Sugiyama… - The journal of …, 2004 - journals.aai.org
Autoimmune disease in Fas-deficient MRL-Fas lpr mice is dependent on infiltrating autoreactive
leukocytes and autoantibodies, and IFN-γ plays an important role in the pathogenesis. …

Successful treatment with retinoids in patients with lupus nephritis

…, H Shimazu, Y Nozaki, M Sugiyama… - American journal of …, 2010 - Elsevier
Lupus nephritis is a major manifestation of systemic lupus erythematosus. Treatment with
such immunosuppressive agents as corticosteroids or cyclophosphamide can decrease the …

Role of endothelial damage in the pathogenesis of interstitial pneumonitis in patients with polymyositis and dermatomyositis.

…, T Yamagata, Y Nozaki, M Sugiyama… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: Polymyositis and dermatomyositis (PM/DM) are often complicated by interstitial
pneumonitis (IP), which is an important cause of death. It has been reported that blood …

All-trans-retinoic acid suppresses interferon-γ and tumor necrosis factor-α; a possible therapeutic agent for rheumatoid arthritis

Y Nozaki, C Tamaki, T Yamagata, M Sugiyama… - Rheumatology …, 2006 - Springer
Objectives: To study the effects of all-trans-retinoic acid (ATRA), we determined the proliferation
and cytokine production by peripheral blood mononuclear cells (PBMCs) and CD4 + T …

Effects of pravastatin in murine collagen-induced arthritis

…, K Kinoshita, Y Nozaki, M Sugiyama… - Rheumatology …, 2007 - Springer
Here we evaluated whether 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins)
have beneficial effects for collagen-induced arthritis (CIA). DBA/1 mice were …

Therapeutic effect of retinoic acid on unilateral ureteral obstruction model

…, H Shimazu, Y Nozaki, M Sugiyama… - Nephron Experimental …, 2011 - karger.com
Background: Retinoic acids, a group of natural and synthetic vitamin A derivatives, have
potent anti-proliferative, anti-inflammatory and anti-fibrotic properties. We investigated the …