Background Osteoarthritis (OA) is a degenerative joint disease involving the cartilage and
many of its surrounding tissues. Disease progression is usually slow but can ultimately lead to …

Sarcopenia is associated with a greater fracture risk. This relationship was originally thought
to be explained by an increased risk of falls in sarcopenic individuals. However, in addition, …

Background We consider the relationships between a clinical and radiological diagnosis of
knee or hip OA and activities of daily-living (ADL) in older adults. Methods Data were …

High blood pressure is a major contributor to the global burden of disease and discovering
novel causal pathways of blood pressure regulation has been challenging. We tested blood …

Objective To evaluate the role of comorbidity and pain in the association between hip/knee
osteoarthritis (OA) with self‐reported as well as performance‐based functional limitations in a …

Background Osteoarthritis (OA), the most common form of arthritis, is a major contributor to
functional impairment and loss of independence in older persons. The European Project on …

Objective To investigate patterns of physical activity in older adults with knee osteoarthritis (OA)
compared to older adults without knee OA across 6 European countries. We expect …

Objective. This study examined whether daily weather conditions, 3-day average weather
conditions, and changes in weather conditions influence joint pain in older people with …

High-resolution peripheral quantitative computed tomography (HR-pQCT) captures novel
aspects of bone geometry, volumetric bone mineral density and offers the ability to measure …

Telomere attrition has been associated with age-related diseases, although causality is
unclear and controversial; low-grade systemic inflammation (inflammaging) has also been …