Objective To examine the safety and efficacy of the interleukin‐1 (IL‐1) receptor antagonist
anakinra as first‐line therapy for systemic juvenile idiopathic arthritis (JIA). Methods Patients …

Background Hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility spectrum
disorders (HSD) are debilitating conditions. Diagnosis is currently clinical in the absence of …

Objective: We undertook an observational study to obtain a complete overview of the long-term
effectiveness and safety of etanercept in patients with different juvenile idiopathic arthritis …

Objective To assess the efficacy, tolerability, and safety of sulfasalazine (SSZ) in the treatment
of juvenile chronic arthritis (JCA). Methods We conducted a 24‐week randomized, placebo…

Objective Children with juvenile idiopathic arthritis (JIA) experience functional impairment
due to joint manifestations of the disease. The aim of our present study was to assess health‐…

Context Since the introduction of biologic therapies, the pharmacological treatment approach
for juvenile idiopathic arthritis (JIA) has changed substantially, with achievement of inactive …

Background Health Related Quality of Life (HRQOL) questionnaires are increasingly used
in clinical practice. These Patient Reported Outcomes (PROs) are provided to the …

Background Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis
(WG), belongs to the group of ANCA-associated necrotizing vasculitides. This study …

Objective. To report on the progress of an ongoing research collaboration on magnetic
resonance imaging (MRI) in juvenile idiopathic arthritis (JIA) and describe the proceedings of a …

BACKGROUND AND OBJECTIVE: Monitoring health-related quality of life (HRQoL) by
using electronic patient-reported outcomes (ePROs) has been only minimally evaluated in …