GRP78: a multifunctional receptor on the cell surface

M GonzalezGronow, MA Selim, J Papalas… - Antioxidants & redox …, 2009 - liebertpub.com
The 78 kDa glucose-regulated protein (GRP78) is an endoplasmic reticulum chaperone,
whose function is generally thought to be restricted to controlling the structural maturation of …

[HTML][HTML] The role of Grp 78 in α2-macroglobulin-induced signal transduction: evidence from RNA interference that the low density lipoprotein receptor-related protein is …

UK Misra, M Gonzalez-Gronow, G Gawdi… - Journal of Biological …, 2002 - ASBMB
The low density lipoprotein receptor-related protein (LRP) is a scavenger receptor that binds
to many proteins, some of which trigger signal transduction. Receptor-recognized forms of α …

Prostate Cancer Cell Proliferation In vitro Is Modulated by Antibodies against Glucose-Regulated Protein 78 Isolated from Patient Serum

M Gonzalez-Gronow, M Cuchacovich, C Llanos… - Cancer research, 2006 - AACR
Circulating autoantibodies against the glucose-regulated protein of 78 kDa (GRP78) are
present at high levels in prostate cancer patients and are a biomarker of aggressive tumor …

The role of MTJ-1 in cell surface translocation of GRP78, a receptor for α2-macroglobulin-dependent signaling

UK Misra, M Gonzalez-Gronow, G Gawdi… - The Journal of …, 2005 - journals.aai.org
MTJ-1 associates with a glucose-regulated protein of M r∼ 78,000 (GRP78) in the endoplasmic
reticulum and modulates GRP78 activity as a chaperone. GRP78 also exists on the cell …

Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders

M GonzalezGronow, U Gopal, RC Austin… - IUBMB life, 2021 - Wiley Online Library
The 78 kDa glucose‐regulated protein (GRP78) is an endoplasmic reticulum (ER)‐resident
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …

Angiostatin's molecular mechanism: aspects of specificity and regulation elucidated

…, DJ Kenan, M GonzalezGronow… - Journal of cellular …, 2005 - Wiley Online Library
Tumor growth requires the development of new vessels that sprout from pre-existing normal
vessels in a process known as ‘‘angiogenesis’’[Folkman (1971) N Engl J Med 285: 1182–…

A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates α2M*-induced signalling

UK Misra, M Gonzalez-Gronow, G Gawdi, F Wang… - Cellular signalling, 2004 - Elsevier
The activated proteinase inhibitor α 2 -macroglobulin (α 2 M*) binds to two receptors, the low
density lipoprotein receptor-related protein (LRP-1) and the α 2 M* signalling receptor (α 2 …

[HTML][HTML] The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells

M Gonzalez-Gronow, T Kalfa, CE Johnson… - Journal of Biological …, 2003 - ASBMB
Human plasminogen contains structural domains that are termed kringles. Proteolytic cleavage
of plasminogen yields kringles 1–3 or 4 and kringle 5 (K5), which regulate endothelial …

Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site

M Gonzalez-Gronow, JM Edelberg, SV Pizzo - Biochemistry, 1989 - ACS Publications
Materials and Methods Proteins. Pg was purified from human plasma by affinity chromatography
on L-lysine-Sepharose (Deutsch & Mertz, 1970). Pg 1 and 2 were separated by affinity …

[PDF][PDF] Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor

M Gonzalez-Gronow, S Kaczowka, G Gawdi… - Front Biosci, 2008 - researchgate.net
GonzalezGronow: Anti-tumor necrosis factor-α therapy augments dipeptidylpeptidase IV activity
and … Gonzalez-Gronow: Neonatal plasminogen displays altered cell surface binding and …