OBJECTIVE: To determine if lowering of serum uric acid (SUA) concentrations below 6 mg/dl
or longer duration of lowered SUA will result in depletion of urate crystals from the knee …

Aliquots from 30 synovial fluids were submitted to 4 laboratories for comparison of leukocyte
counts and differential cell counts, and to 3 laboratories for a search for and identification of …

Objective. In this in vivo study, we investigated changes in the proteins that coat monosodium
urate (MSU) crystals in human synovial fluid samples and rat air pouch fluid samples …

OBJECTIVE: This survey was designed to examine features of a group of patients with acute
painful joint effusions following hylan GF 20 (Synvisc) knee injections. METHODS: Eight …

Objective. Reasons for apparent primary deposition of calcium pyrophosphate dihydrate (CPPD)
crystals in some synovial membranes have not been systematically examined. We …

METHODS The protocol was reviewed and approved by the Institutional Review Board of
the Department of Veterans Affairs Medical Center, Philadelphia. Sixteen male patients with …

A solution containing synthetic liposomes was injected into rabbit knee joints. This induced
light and electron microscopic findings very similar to those seen in acute or chronic arthritis, …

OBJECTIVE: To examine the ability of rofecoxib prophylaxis to blunt the effect of monosodium
urate (MSU) crystal inflammation induced in the rat subcutaneous air pouch. METHODS: …

Rapidly destructive arthritis with relatively noninflammatory joint fluids has been described
at shoulders as well as at other large joints under a variety of names in older persons. …

Studies by light microscopy on synovium obtained from 11 patients with Reiter's syndrome
during the first month of an episode showed proliferation of synovial lining cells, …